The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Cell Res. 2012 Dec;22(12):1624-6. doi: 10.1038/cr.2012.109. Epub 2012 Jul 17.
The laboratories of Galina Petukhova and R Daniel Camerini-Otero have achieved significant technical advances in determining the genome-wide sites of DNA double-strand breaks (DSBs) where the process of genetic exchange between chromatids during meiosis begins. Applying the new approaches to male meiosis in mice, their experimental results considerably increase our insights into the nature and regulation of these processes.
加利娜·彼得科娃（Galina Petukhova）和 R 丹尼尔·卡梅里尼-奥特罗（R Daniel Camerini-Otero）的实验室在确定染色体在减数分裂过程中发生遗传交换的 DNA 双链断裂（DSBs）的全基因组位点方面取得了重大技术进展。他们将新方法应用于雄性减数分裂的小鼠实验中，实验结果大大提高了我们对这些过程的本质和调控的认识。
