Anikpeh Y Flammer, Keller P, Bloemberg G V, Grünenfelder J, Zinkernagel A S
Division of Infectious Diseases, University Hospital Zurich, Zurich, Switzerland. yvonne.fl
BMJ Case Rep. 2010 Dec 29;2010:bcr0620103058. doi: 10.1136/bcr.06.2010.3058.
In a patient with mediastinitis after cardiac surgery Paenibacillus pasadenensis was detected in his sternal wound. Paenibacilli are gram-positive, aerobic, bacteria related to bacilli. Until recently these organisms were not known to cause human disease. A few cases of human infection caused by another member of this genus, P alvei, have been reported. The authors describe the first infection with P pasadenensis in humans. P pasadenensis was detected by broad-range bacterial 16S rRNA PCR. Treatment consisted of surgical debridement and antibiotics, vancomycin and ciprofloxacin followed by clindamycin and ciprofloxacin, resulting in complete recovery.
在一名心脏手术后发生纵隔炎的患者的胸骨伤口中检测到帕萨迪纳类芽孢杆菌。类芽孢杆菌是革兰氏阳性需氧菌，与芽孢杆菌属相关。直到最近，这些微生物还不被认为会导致人类疾病。已经报道了由该属的另一个成员蜂房类芽孢杆菌引起的几例人类感染病例。作者描述了首例人类感染帕萨迪纳类芽孢杆菌的病例。通过广谱细菌16S rRNA聚合酶链反应检测到帕萨迪纳类芽孢杆菌。治疗包括手术清创和使用抗生素，先使用万古霉素和环丙沙星，随后使用克林霉素和环丙沙星，最终患者完全康复。
