ARTORG Center for Biomedical Engineering Research, University of Bern, 3010, Bern, Switzerland.
Ann Biomed Eng. 2013 Jan;41(1):131-41. doi: 10.1007/s10439-012-0623-3. Epub 2012 Jul 18.
Energy-harvesting devices attract wide interest as power supplies of today's medical implants. Their long lifetime will spare patients from repeated surgical interventions. They also offer the opportunity to further miniaturize existing implants such as pacemakers, defibrillators or recorders of bio signals. A mass imbalance oscillation generator, which consists of a clockwork from a commercially available automatic wrist watch, was used as energy harvesting device to convert the kinetic energy from the cardiac wall motion to electrical energy. An MRI-based motion analysis of the left ventricle revealed basal regions to be energetically most favorable for the rotating unbalance of our harvester. A mathematical model was developed as a tool for optimizing the device's configuration. The model was validated by an in vitro experiment where an arm robot accelerated the harvesting device by reproducing the cardiac motion. Furthermore, in an in vivo experiment, the device was affixed onto a sheep heart for 1 h. The generated power in both experiments-in vitro (30 μW) and in vivo (16.7 μW)-is sufficient to power modern pacemakers.
能量收集装置作为当今医疗植入物的电源引起了广泛关注。它们的长寿命将使患者免于反复的手术干预。它们还为进一步缩小现有的植入物,如起搏器、除颤器或生物信号记录器,提供了机会。一个由市售自动手表的发条组成的质量不平衡振荡发电机被用作能量收集装置,将来自心肌壁运动的动能转换为电能。基于 MRI 的左心室运动分析显示,基底区域对于我们的收集器的旋转不平衡是最有利的。开发了一个数学模型作为优化设备配置的工具。该模型通过体外实验得到验证,其中一个手臂机器人通过再现心脏运动来加速采集器。此外,在体内实验中,该设备被固定在绵羊心脏上 1 小时。在体外实验(30 μW)和体内实验(16.7 μW)中产生的功率足以为现代起搏器供电。