Department of Oncology, King Fahad Hospital, Madina, Saudi Arabia.
J Breast Cancer. 2012 Jun;15(2):244-7. doi: 10.4048/jbc.2012.15.2.244. Epub 2012 Jun 28.
Metastasis to the breast from extra-mammary tumors is rare with only a few sporadic cases reported. We present a 58-year-old female patient diagnosed with renal cell carcinoma. Five years ago she had a radical nephrectomy and was free of disease, then discovered solitary breast mass following self-examination. The patient presented to the breast clinic for evaluation whereupon the breast mass was identified on physical and radiological examinations. Fine needle aspiration was diagnostic of metastatic renal cell carcinoma and subsequent imaging studies demonstrated multiple pulmonary deposits and recurrent renal mass in the tumor bed of the diseased site. In a multidisciplinary clinic, the patient was elected for excision biopsy followed by systemic tyrosine kinase inhibitor therapy. Six months later she had brain metastasis and received whole brain irradiation followed by palliative therapy. We are presenting this rare case with the aim of increasing awareness of breast secondaries.
乳房转移来自于乳腺外肿瘤较为罕见，仅有少数散发病例报道。我们报告一例 58 岁女性患者，诊断为肾细胞癌。五年前她接受了根治性肾切除术，无疾病，随后在自我检查中发现孤立性乳腺肿块。患者因乳房肿块就诊于乳腺科，经体格检查和影像学检查发现了乳腺肿块。细针抽吸术诊断为转移性肾细胞癌，随后的影像学研究显示多个肺部沉积物和患病部位肿瘤床的复发性肾肿块。在多学科诊所，患者选择进行切除活检，随后进行全身酪氨酸激酶抑制剂治疗。六个月后，她发生脑转移，接受了全脑放疗和姑息治疗。我们报告这个罕见病例旨在提高对乳房继发性肿瘤的认识。
