Uzbekov M G, Alferova V V, Misionzhnik E Y, Gekht A B
Moscow Institute of Psychiatry, Federal Agency for Health Care and Social Development, Russian State Medical University, Moscow, Russia.
Bull Exp Biol Med. 2011 Dec;152(2):195-7. doi: 10.1007/s10517-011-1486-6.
We studied monoamine oxidase activity (MAO) in platelets of patients in the acute period of ischemic stroke. Neurological deficit was evaluated by the data of clinical examinations and scales. In 80% patients MAO activity was considerably increased on 3-5 day after stroke. We found a correlation between increased MAO activity on 3-5 day after ischemic stroke and regression of neurological deficit on day 21 after ischemic stroke. The increase in MAO activity during the acute period of ischemic stroke is presumably a compensatory response aimed at stabilization of tissue homeostasis.
