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小檗属植物的植物化学和药理学应用。

Phyto-chemical and pharmacological applications of Berberis aristata.

机构信息

CSIR Unit for Research and Development of Information Products Jopasana, Kothrud, Pune, India.

出版信息

Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012.

DOI:10.1016/j.fitote.2012.04.012
PMID:22808523
Abstract

In the recent years, the interest and research in medicinal plants have increased in a great deal. Ayurvedic medicines and formulations developed from ancient Indian herbal systems are renowned for their various important applications. Berberis aristata - an Indian medicinal plant, which belongs to the family Berberidaceae is an ayurvedic herb used since ancient times. It is also known as Indian berberi, Daruharidra, Daruhaldi, Darvi and Chitra. The plant is useful as anti-pyretic, anti-bacterial, anti-microbial, anti-hepatotoxic, anti-hyperglycaemic, anti-cancer, anti-oxidant and anti-lipidemic agent. B. aristata extracts and its formulations are also useful in the treatment of diarrhoea, haemorrhoids, gynaecological disorders, HIV-AIDS, osteoporosis, diabetes, eye and ear infections, wound healing, jaundice, skin diseases and malarial fever. This review aims to highlight the ethnobotany, pharmacognosy and pharmacological uses of B. aristata which will give insights in developing potentially new bioactives from the plant scaffolds. This review will also highlight the patenting trends, the new compositions developed using the actives from B. aristata and the different assignees involved in filing patents.

摘要

近年来,人们对药用植物的兴趣和研究大大增加。源自古印度草药系统的阿育吠陀药物和配方以其各种重要应用而闻名。小檗属植物——一种属于小檗科的印度药用植物,自古以来就是一种阿育吠陀草药。它也被称为印度小檗、达鲁哈里德拉、达鲁阿尔迪、达维维和奇特拉。这种植物具有退热、抗菌、抗微生物、抗肝毒性、降血糖、抗癌、抗氧化和抗脂质作用。B. aristata 提取物及其制剂也可用于治疗腹泻、痔疮、妇科疾病、HIV-AIDS、骨质疏松症、糖尿病、眼部和耳部感染、伤口愈合、黄疸、皮肤病和疟疾发热。本综述旨在强调 B. aristata 的民族植物学、生药学和药理学用途,这将为从植物支架中开发潜在的新生物活性物质提供见解。本综述还将重点介绍专利趋势、使用 B. aristata 中的活性成分开发的新组合物以及参与专利申请的不同受让人。

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