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与吞食蚯蚓和壁虎相关的内脏幼虫移行症:一例报告

Visceral larva migrans associated with earthworm and gecko ingestion: a case report.

作者信息

Yu Tao, Zhao Li-Na, Fan Miao-Jing, Wu Huan, Chen Qi-Kui

机构信息

Department of Gastroenterology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yan Jiang Xi Road, Guangzhou, 510120, People's Republic of China.

出版信息

J Med Case Rep. 2012 Jul 18;6:210. doi: 10.1186/1752-1947-6-210.

DOI:10.1186/1752-1947-6-210
PMID:22809241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3408347/
Abstract

INTRODUCTION

Visceral larva migrans is a syndrome caused by an infection with larval helminths, which may result in partial or general pathological changes in host tissues. Due to the difficulty in finding the causative parasites, the diagnosis of visceral larva migrans is generally based on compatible clinical signs, epidemic history, marked eosinophilia and pathological examination, especially positive serological test results and the disappearance of symptoms after specific treatment.

CASE PRESENTATION

We report here the case of a 21-year-old Chinese man who, having ingested living earthworms and geckos at a witch's suggestion, presented with fatigue and wordlessness lasting for one year along with elevated transaminase levels for one month. Clinical examination showed eosinophilia, elevated transaminase levels, nodular lesions in his liver and typical pathological characteristics of hepatic visceral larva migrans. After four courses of anthelmintic therapy, our patient presented with sustaining improvement of clinical manifestations and normalization of laboratory data.

CONCLUSIONS

Because of the difficulty in making a definite diagnosis, anthelmintic therapy should be performed in patients with a suspected diagnosis of visceral larva migrans based on their epidemic history and presence of typical manifestations, especially when the serological test results are negative. Furthermore, patients with severe parasite infection may require multiple anthelmintic therapies in order to eliminate the parasites.

摘要

引言

内脏幼虫移行症是由幼虫期蠕虫感染引起的一种综合征,可导致宿主组织出现局部或全身病理变化。由于难以找到致病寄生虫,内脏幼虫移行症的诊断通常基于相符的临床症状、流行病史、明显的嗜酸性粒细胞增多以及病理检查,尤其是血清学检测结果阳性和特异性治疗后症状消失。

病例报告

我们在此报告一名21岁中国男性的病例,该患者在巫师的建议下吞食了活蚯蚓和壁虎,出现疲劳和不语症状达一年,转氨酶水平升高一个月。临床检查显示嗜酸性粒细胞增多、转氨酶水平升高、肝脏出现结节性病变以及肝内脏幼虫移行症的典型病理特征。经过四个疗程的驱虫治疗后,我们的患者临床表现持续改善,实验室数据恢复正常。

结论

由于难以做出明确诊断,对于根据流行病史和典型表现疑似内脏幼虫移行症的患者应进行驱虫治疗,尤其是血清学检测结果为阴性时。此外,严重寄生虫感染的患者可能需要多次驱虫治疗以清除寄生虫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/3408347/d28371768b62/1752-1947-6-210-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/3408347/3b43a57ccb76/1752-1947-6-210-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/3408347/d28371768b62/1752-1947-6-210-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/3408347/3b43a57ccb76/1752-1947-6-210-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92c0/3408347/d28371768b62/1752-1947-6-210-2.jpg

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