Bignami M, Aulicino F, Velcich A, Carere A, Morpurgo G
Mutat Res. 1977 Dec;46(6):395-402. doi: 10.1016/0165-1161(77)90017-6.
Thirteen pesticides, aminotriazole, benomyl, captafol, captan, dalapon-Na, dichlorvos, dinobuton, dodine, ioxynil, mecoprop, neburon, picloram and tordon were tested for ability to induce (1) point mutations to 8-azaguanine resistance, (2) mitotic crossing-over, and (3) mitotic non-disjunction and haploidization in Aspergillus nidulans. Tests were performed at three different pHs, i.e. 4.5, 7, 8.2. Three of the pesticides, captan , captafol and dichlorvos induced point mutations; dichlorvos also induced a high frequency of mitotic crossing-over and non-disjunction; benomyl induced a very high frequency of non-disjunction whereas aminotriazole induced weakly both types of somatic segregation.
对13种农药，即氨三唑、苯菌灵、克菌丹、敌菌丹、茅草枯钠、敌敌畏、二硝巴豆酚、多果定、碘苯腈、甲氧丙酸、绿谷隆、毒莠定和茅草枯进行了测试，以考察它们在构巢曲霉中诱导(1)对8-氮杂鸟嘌呤抗性的点突变、(2)有丝分裂交换和(3)有丝分裂不分离和单倍体化的能力。测试在三种不同的pH值下进行，即4.5、7、8.2。其中三种农药，即敌菌丹、克菌丹和敌敌畏诱导了点突变；敌敌畏还诱导了高频的有丝分裂交换和不分离；苯菌灵诱导了非常高频率的不分离，而氨三唑对两种类型的体细胞分离诱导作用较弱。
