Division of Global Health Equity, Brigham and Women's Hospital, Boston, MA 02115, USA.
Am J Trop Med Hyg. 2012 Sep;87(3):399-406. doi: 10.4269/ajtmh.2012.12-0036. Epub 2012 Jul 23.
Among tuberculosis patients, timely diagnosis of human immunodeficiency virus (HIV) co-infection and early antiretroviral treatment are crucial, but are hampered by a myriad of individual and structural barriers. Community-based models to provide counseling and rapid HIV testing are few but offer promise. During November 2009-April 2010, community health workers offered and performed HIV counseling and testing by using the OraQuick Rapid HIV-1/2 Antibody Test to new tuberculosis cases in 22 Ministry of Health establishments and their household contacts (n = 130) in Lima, Peru. Refusal of HIV testing or study participation was low (4.7%). Intervention strengths included community-based approach with participant preference for testing site, use of a rapid, non-invasive test, and accompaniment to facilitate HIV care and family disclosure. We will expand the intervention under programmatic auspices for rapid community-based testing for new tuberculosis cases in high incidence establishments. Other potential target populations include contacts of HIV-positive persons and pregnant women.
在结核病患者中,及时诊断人类免疫缺陷病毒(HIV)合并感染并尽早进行抗逆转录病毒治疗至关重要,但由于各种个人和结构障碍而受到阻碍。提供咨询和快速 HIV 检测的基于社区的模式很少,但有希望。2009 年 11 月至 2010 年 4 月期间,社区卫生工作者向秘鲁利马的 22 个卫生部下属机构及其家庭接触者(n=130)中新发现的结核病患者提供并进行了 HIV 咨询和检测,采用的是 OraQuick 快速 HIV-1/2 抗体检测。拒绝 HIV 检测或参与研究的比例很低(4.7%)。干预的优势包括基于社区的方法,让参与者自行选择检测地点,使用快速、非侵入性的检测方法,并提供陪伴,以促进 HIV 护理和家庭披露。我们将在方案的支持下扩大干预范围,为高发病率机构中新发现的结核病患者提供快速的基于社区的检测。其他潜在的目标人群包括 HIV 阳性者的接触者和孕妇。