Diabetes Obes Metab. 2013 Jan;15(1):87-90. doi: 10.1111/j.1463-1326.2012.01668.x. Epub 2012 Aug 22.
Previous research shows diminished weight loss success in insulin-resistant (IR) women assigned to a low-fat (LF) diet compared to those assigned to a low-carbohydrate (LC) diet. These secondary analyses examined the relationship between insulin-resistance status and dietary adherence to either a LF-diet or LC-diet among 81 free-living, overweight/obese women [age = 41.9 ± 5.7 years; body mass index (BMI) = 32.6 ± 3.6 kg/m(2)]. This study found differential adherence by insulin-resistance status only to a LF-diet, not a LC-diet. IR participants were less likely to adhere and lose weight on a LF-diet compared to insulin-sensitive (IS) participants assigned to the same diet. There were no significant differences between IR and IS participants assigned to LC-diet in relative adherence or weight loss. These results suggest that insulin resistance status may affect dietary adherence to weight loss diets, resulting in higher recidivism and diminished weight loss success of IR participants advised to follow LF-diets for weight loss.
先前的研究表明，与接受低碳水化合物（LC）饮食的患者相比，胰岛素抵抗（IR）女性接受低脂肪（LF）饮食的减肥成功率降低。这些二次分析检查了在 81 名自由生活、超重/肥胖女性中（年龄 = 41.9 ± 5.7 岁；体重指数（BMI）= 32.6 ± 3.6 kg/m(2)），IR 状态与对 LF 饮食或 LC 饮食的饮食依从性之间的关系。这项研究发现，IR 参与者对 LF 饮食的依从性较差，而不是 LC 饮食。与分配到相同饮食的胰岛素敏感（IS）参与者相比，IR 参与者不太可能坚持并减轻 LF 饮食的体重。分配到 LC 饮食的 IR 和 IS 参与者在相对依从性或体重减轻方面没有显着差异。这些结果表明，胰岛素抵抗状态可能会影响减肥饮食的饮食依从性，导致建议遵循 LF 饮食减肥的 IR 参与者的复发率更高，减肥成功率降低。
