Setor de Parasitologia, Instituto Evandro Chagas, Belém, PA, Brasil.
Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):453-6. doi: 10.1590/s0037-86822012005000007. Epub 2012 Jul 26.
In Brazil, studies have shown that HTLV seroprevalence among pregnant women varies from 0 to 1.8%. However, this seroprevalence was unknown in the State of Pará, Brazil. The present study describes, for the first time, the HTLV seroprevalence among pregnant women from the State of Pará, Northern Brazil.
13,382 pregnant women were submitted to HTLV screening during prenatal care, and those with non-seronegative results to anti-HTLV were submitted to Western blot (WB) test to confirm and separate HTLV-1 and HTLV-2 carriers.
HTLV seroprevalence in the population of pregnant women was 0.3%, and HTLV-1 was identified in 95.3% of patients. The demographic profile of HTLV carriers was as follows: women with age between 20 and 40 years old (78.4%); residing in the metropolitan region of Belém, Pará (67.6%); and with educational level of high school (56.8%). Other variables related to infection were as follows: beginning of sexual intercourse between the age of 12 and 18 years old (64.9%) and have being breastfed for more than 6 months (51.4%). Most of the women studied had at least two previous pregnancies (35.1%) and no abortion (70.3%). Coinfections (syphilis and HIV) were found in 10.8% (4/37) of these pregnant women.
Seroprevalence of HTLV infection in pregnant women assisted in basic health units from the State of Pará, Northern Brazil, was 0.3% similar to those described in other Brazilian studies. The variables related to infection were important indicators in identifying pregnant women with a higher tendency to HTLV seropositivity, being a strategy for disease control and prevention, avoiding vertical transmission.
在巴西，研究表明孕妇的 HTLV 血清流行率在 0 到 1.8%之间变化。然而，在巴西帕拉州，这种血清流行率尚不清楚。本研究首次描述了巴西北部帕拉州孕妇的 HTLV 血清流行率。
在产前保健期间，对 13382 名孕妇进行了 HTLV 筛查，对非阴性结果的抗 HTLV 孕妇进行了 Western blot（WB）检测，以确认和分离 HTLV-1 和 HTLV-2 携带者。
孕妇人群中的 HTLV 血清流行率为 0.3%，其中 95.3%的患者为 HTLV-1 感染者。HTLV 携带者的人口统计学特征如下：年龄在 20 至 40 岁之间的女性（78.4%）；居住在帕拉州贝伦大都市区（67.6%）；以及高中教育水平（56.8%）。与感染相关的其他变量如下：12 至 18 岁开始性行为（64.9%）和母乳喂养超过 6 个月（51.4%）。研究中的大多数女性至少有两次既往妊娠（35.1%），且无流产（70.3%）。这些孕妇中有 10.8%（4/37）合并感染（梅毒和 HIV）。
在巴西北部基本保健单位接受检查的孕妇中，HTLV 感染的血清流行率为 0.3%，与巴西其他研究中描述的流行率相似。感染相关的变量是确定具有更高 HTLV 血清阳性倾向的孕妇的重要指标，是控制和预防疾病的策略，可避免垂直传播。
