Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Emerg Infect Dis. 2012 Aug;18(8):1326-8. doi: 10.3201/eid1808.111686.
Vibrio cholerae resistance to third-generation cephalosporins is rarely reported. We detected a strain that was negative for extended-spectrum β-lactamase and positive for the AmpC disk test, modified Hodge test, and EDTA disk synergy test and harbored the blaDHA-1 and blaNDM-1 genes. The antimicrobial drug susceptibility profile of V. cholerae should be monitored.
霍乱弧菌对第三代头孢菌素的耐药性很少见。我们检测到一株既对超广谱β-内酰胺酶阴性,又对头孢西丁纸片扩散试验、改良 Hodge 试验和 EDTA 协同纸片增效试验阳性,同时携带 blaDHA-1 和 blaNDM-1 基因的菌株。应监测霍乱弧菌的抗菌药物药敏谱。