Leveque B, Rousseau A, Gourmelen M
Sem Hop. 1979;55(31-32):1407-14.
Two patients with dwarfism were found to have intolerance to gluten. The authors describe the clinical, biological and radiological signs which enable the growth disorder to be related to its true cause, when obvious signs of a celiac syndrome are lacking. In fact, a small intestine biopsy is the essential diagnostic procedure. The hormonal changes found in such patients are discussed, and include normal HGH levels, reduced somatomedin activity which becomes normal after a gluten-free diet, and low blood insulin levels in the basal state as in insulin tolerance tests.
两名侏儒症患者被发现对麸质不耐受。作者描述了在缺乏腹腔疾病综合征明显体征时,能够将生长障碍与其真正病因相关联的临床、生物学和放射学体征。实际上,小肠活检是必不可少的诊断程序。文中讨论了此类患者发现的激素变化,包括生长激素(HGH)水平正常、生长调节素活性降低(无麸质饮食后恢复正常)以及基础状态下血胰岛素水平低(如同胰岛素耐量试验)。