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两例表现为侏儒症的麸质不耐受病例(作者译)

[Two cases of gluten intolerance presenting as dwarfism (author's transl)].

作者信息

Leveque B, Rousseau A, Gourmelen M

出版信息

Sem Hop. 1979;55(31-32):1407-14.

PMID:228420
Abstract

Two patients with dwarfism were found to have intolerance to gluten. The authors describe the clinical, biological and radiological signs which enable the growth disorder to be related to its true cause, when obvious signs of a celiac syndrome are lacking. In fact, a small intestine biopsy is the essential diagnostic procedure. The hormonal changes found in such patients are discussed, and include normal HGH levels, reduced somatomedin activity which becomes normal after a gluten-free diet, and low blood insulin levels in the basal state as in insulin tolerance tests.

摘要

两名侏儒症患者被发现对麸质不耐受。作者描述了在缺乏腹腔疾病综合征明显体征时,能够将生长障碍与其真正病因相关联的临床、生物学和放射学体征。实际上,小肠活检是必不可少的诊断程序。文中讨论了此类患者发现的激素变化,包括生长激素(HGH)水平正常、生长调节素活性降低(无麸质饮食后恢复正常)以及基础状态下血胰岛素水平低(如同胰岛素耐量试验)。

相似文献

1
[Two cases of gluten intolerance presenting as dwarfism (author's transl)].两例表现为侏儒症的麸质不耐受病例(作者译)
Sem Hop. 1979;55(31-32):1407-14.
2
[Two cases of gluten intolerance presenting as dwarfism].[两例表现为侏儒症的麸质不耐受病例]
Ann Pediatr (Paris). 1979 Feb;26(2):91-8.
3
[Coeliac dwarfism. Hormonal and growth studies in late diagnosed gluten intolerance (author's transl)].[乳糜泻侏儒症。晚期诊断出的麸质不耐受的激素及生长研究(作者译)]
Ann Pediatr (Paris). 1980 Feb;27(2):101-8.
4
Gluten tolerance in adult patients with celiac disease 20 years after diagnosis?乳糜泻成年患者确诊20年后的麸质耐受性?
Eur J Gastroenterol Hepatol. 2008 May;20(5):423-9. doi: 10.1097/MEG.0b013e3282f4de6e.
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Celiac disease.乳糜泻
J Pediatr Gastroenterol Nutr. 2008 Aug;47 Suppl 1:S3-6. doi: 10.1097/MPG.0b013e3181818df5.
6
[Dwarfism in the Alagille syndrome caused by somatomedin C deficiency?].[生长调节素C缺乏导致阿拉吉列综合征中的侏儒症?]
Padiatr Padol. 1986;21(3):257-64.
7
[Diagnostic value of the histological examination in gluten-sensitive enteropathy].[组织学检查在麸质敏感性肠病中的诊断价值]
Morphol Igazsagugyi Orv Sz. 1981 Apr;21(2):142-9.
8
[The provocation test in children with cow-milk protein and gluten intolerance: evaluation of the clinical response and lesions in the mucous membrane of the small intestine].[牛奶蛋白和麸质不耐受儿童的激发试验:小肠黏膜临床反应及病变评估]
Pol Tyg Lek. 1990;45(8-9):161-5.
9
[Severe dwarfism with high plasma hGH levels and no somatomedin acitvity: Laron's syndrome (author's transl)].严重侏儒症伴高血浆人生长激素水平且无生长调节素活性:拉龙综合征(作者译)
Sem Hop. 1980;56(43-44):1853-6.
10
[Activity of blood somatomedin during childhood in normal subjects and in delayed growth].
Ann Biol Clin (Paris). 1976;34(1):11-8.

引用本文的文献

1
Effects of a gluten-free diet on catch-up growth and height prognosis in coeliac children with growth retardation recognized after the age of 5 years.无麸质饮食对5岁后确诊的患有生长发育迟缓的腹腔疾病儿童追赶生长及身高预后的影响。
Eur J Pediatr. 1988 Feb;147(2):188-91. doi: 10.1007/BF00442220.
2
Growth failure and insulin-like growth factor (IGF-I) in childhood celiac disease.儿童乳糜泻中的生长发育迟缓与胰岛素样生长因子(IGF-I)
Klin Wochenschr. 1991 Nov 15;69(18):825-9. doi: 10.1007/BF01649453.