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运动诱导的血管内皮适应性信号：对心血管疾病的影响

Exercise-induced Signals for Vascular Endothelial Adaptations: Implications for Cardiovascular Disease.

作者信息

Jenkins Nathan T, Martin Jeffrey S, Laughlin M Harold, Padilla Jaume

机构信息

Biomedical Sciences, University of Missouri, Columbia, MO.

出版信息

Curr Cardiovasc Risk Rep. 2012 Aug 1;6(4):331-346. doi: 10.1007/s12170-012-0241-5.

DOI:10.1007/s12170-012-0241-5
PMID:22844545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3404842/
Abstract

This article reviews recent advances in our understanding of hemodynamic signals, external/compressive forces, and circulating factors that mediate exercise training-induced vascular adaptations, with particular attention to the roles of these signals in prevention and treatment of endothelial dysfunction and cardiovascular (CV) diseases.

摘要

本文综述了我们对血流动力学信号、外部/压力性力量以及循环因子的最新认识进展，这些因素介导了运动训练诱导的血管适应性变化，尤其关注这些信号在预防和治疗内皮功能障碍及心血管疾病中的作用。

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本文引用的文献

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Peripheral circulation.外周循环。
Compr Physiol. 2012 Jan;2(1):321-447. doi: 10.1002/cphy.c100048.
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Brachial artery adaptation to lower limb exercise training: role of shear stress.肱动脉对下肢运动训练的适应：切应力的作用。
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Intermittent pneumatic leg compressions enhance muscle performance and blood flow in a model of peripheral arterial insufficiency.间歇性气动腿部压缩可增强外周动脉功能不全模型中的肌肉性能和血流。
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Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.体外反搏增强治疗可改善糖代谢异常患者的外周动脉功能和葡萄糖耐量。
J Appl Physiol (1985). 2012 Mar;112(5):868-76. doi: 10.1152/japplphysiol.01336.2011. Epub 2011 Dec 22.
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Adaptive response of vascular endothelial cells to an acute increase in shear stress magnitude.血管内皮细胞对切应力幅度急性增加的适应反应。
Am J Physiol Heart Circ Physiol. 2012 Feb 15;302(4):H983-91. doi: 10.1152/ajpheart.00168.2011. Epub 2011 Dec 2.
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Stem cells and the vasculature.干细胞与脉管系统。
Nat Med. 2011 Nov 7;17(11):1437-43. doi: 10.1038/nm.2539.
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Mechanotransduction of shear in the endothelium: basic studies and clinical implications.内皮细胞切变力的转导：基础研究与临床意义。
Vasc Med. 2011 Oct;16(5):365-77. doi: 10.1177/1358863X11422109.
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Brachial artery vasodilatation during prolonged lower limb exercise: role of shear rate.长时间下肢运动期间肱动脉血管舒张：切变率的作用。
Exp Physiol. 2011 Oct;96(10):1019-27. doi: 10.1113/expphysiol.2011.059584. Epub 2011 Jul 22.
9
Seven days of aerobic exercise training improves conduit artery blood flow following glucose ingestion in patients with type 2 diabetes.7 天的有氧运动训练可改善 2 型糖尿病患者葡萄糖摄入后的导引导管动脉血流。
J Appl Physiol (1985). 2011 Sep;111(3):657-64. doi: 10.1152/japplphysiol.00489.2011. Epub 2011 Jul 7.
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Effects of acute and chronic endurance exercise on intracellular nitric oxide and superoxide in circulating CD34⁺ and CD34⁻ cells.急慢性耐力运动对循环 CD34⁺和 CD34⁻细胞内一氧化氮和超氧阴离子的影响。
J Appl Physiol (1985). 2011 Sep;111(3):929-37. doi: 10.1152/japplphysiol.00541.2011. Epub 2011 Jun 23.