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预测结肠憩室再出血的因素:111 例患者临床和结肠镜特征的回顾性分析。

Predictive factors for colonic diverticular rebleeding: a retrospective analysis of the clinical and colonoscopic features of 111 patients.

机构信息

Department of Gastroenterology, Aso Iizuka Hospital, Iizuka, Japan.

出版信息

Gut Liver. 2012 Jul;6(3):334-8. doi: 10.5009/gnl.2012.6.3.334. Epub 2012 Jul 12.

Abstract

BACKGROUND/AIMS: Colonic diverticular bleeding can stop spontaneously or be stopped by endoscopic hemostasis. We analyzed the clinical and colonoscopic features of patients with colonic diverticular bleeding to establish the predictive factors for rebleeding.

METHODS

A total of 111 patients (median age, 72 years) with colonic diverticular bleeding in Aso Iizuka Hospital between April 2007 and July 2010 were enrolled. Age, sex, body mass index (BMI), comorbidity, medication, location of bleeding, colonoscopic findings and hemostatic methods were analyzed retrospectively from the hospital records.

RESULTS

The most common sites of bleeding were the ascending (39.6%) and sigmoid (29.7%) colon. Overt rebleeding occurred in 30 patients (27.0%). Spontaneous hemostasis was seen in 81 patients (73.0%), and endoscopic hemostatic treatment was performed in 30 patients. The BMI in the patients with colonic diverticular rebleeding was significantly higher than in patients without rebleeding. Colonoscopic findings of actively bleeding or nonbleeding visible vessels in the responsible diverticula were more frequent in the group with rebleeding.

CONCLUSIONS

A higher BMI and colonoscopic findings of actively bleeding or nonbleeding visible vessels can be used as predictive factors for colonic diverticular rebleeding. Patients with such findings should be carefully followed up after hemostasis of the initial colonic diverticular bleeding.

摘要

背景/目的:结肠憩室出血可自行停止或通过内镜止血。我们分析了结肠憩室出血患者的临床和结肠镜特征,以确定再出血的预测因素。

方法

2007 年 4 月至 2010 年 7 月期间,在 Aso Iizuka 医院共收治 111 例(中位年龄 72 岁)结肠憩室出血患者。回顾性分析从医院记录中获得的年龄、性别、体重指数(BMI)、合并症、药物治疗、出血部位、结肠镜检查结果和止血方法。

结果

最常见的出血部位是升结肠(39.6%)和乙状结肠(29.7%)。30 例患者(27.0%)出现显性再出血。81 例患者(73.0%)自发性止血,30 例患者行内镜止血治疗。结肠憩室再出血患者的 BMI 明显高于无再出血患者。再出血组中,责任憩室有活动性出血或无出血可见血管的结肠镜检查结果更为常见。

结论

较高的 BMI 和结肠镜下有活动性出血或无出血可见血管的表现可作为结肠憩室再出血的预测因素。对于这些有阳性发现的患者,在初始结肠憩室出血止血后应密切随访。

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