Oster S E, Chirurgi V A, Goldberg A A, Aiken S, McCabe R E
Medical Service, Veterans Administration Medical Center, Martinez, California 94553.
Antimicrob Agents Chemother. 1990 Sep;34(9):1821-3. doi: 10.1128/AAC.34.9.1821.
A prospective review of all enterococcal isolates for 13 months showed that 9.0% were resistant to ampicillin (MIC, greater than or equal to 16 micrograms/ml; zone diameter, less than 15 mm), as determined by the Vitek system, disk diffusion, microdilution MIC testing, and macrodilution MIC testing. All were beta-lactamase negative. A total of 19 and 3 resistant isolates were from urine and intravascular sites, respectively. Ampicillin-resistant enterococci appear to be a growing clinical problem.
对所有肠球菌分离株进行的为期13个月的前瞻性评估表明,根据Vitek系统、纸片扩散法、微量稀释法MIC检测和常量稀释法MIC检测,9.0%的分离株对氨苄西林耐药(MIC大于或等于16微克/毫升;抑菌圈直径小于15毫米)。所有分离株均为β-内酰胺酶阴性。分别有19株和3株耐药分离株来自尿液和血管内部位。耐氨苄西林肠球菌似乎是一个日益严重的临床问题。