Department of Periodontology, School of Dentistry, University of Novafapi, Teresina, Piauí, Brazil.
Eur J Clin Microbiol Infect Dis. 2013 Jan;32(1):27-32. doi: 10.1007/s10096-012-1710-y. Epub 2012 Aug 3.
The aim of this study was to evaluate if the presence of periodontal infections (PI) is associated with community-acquired pneumonia (CAP) in a group of patients admitted to a hospital. A total of 140 patients were enrolled in this case-control study, with 70 patients having CAP (case group) and the other 70 patients diagnosed with other systemic diseases (control group). A periodontal examination was carried out to assess pocket probing depth (PPD), clinical attachment loss (CAL), bleeding on probing (BOP), and presence of bacterial plaque (BP). CAL and BOP showed higher scores in the case group over the control group. They were, respectively, 3.16 ± 2.43 mm and 0.33 ± 0.24 % for the case group, and 1.99 ± 2.23 mm and 0.25 ± 0.24 % for the control group (p < 0.05). High scores for BP were observed in both groups (case: 97.1 %; control: 98.6 %, p = 1.0000). Chronic periodontitis (CP) was more frequent in patients with CAP (case: 61.4 %; control: 41.4 %). The presence of moderate or severe CP increased the risk for CAP [odds ratio (OR) = 4.4, 95 % confidence interval (CI) = 1.4-13.8], even when adjusted for age, ethnicity, gender, and smoking. Moderate and severe chronic periodontitis were associated with CAP in this study.
本研究旨在评估牙周感染（PI）是否与一组住院患者的社区获得性肺炎（CAP）有关。这项病例对照研究共纳入了 140 名患者，其中 70 名患有 CAP（病例组），另外 70 名患有其他系统性疾病（对照组）。进行牙周检查以评估探诊深度（PPD）、临床附着丧失（CAL）、探诊出血（BOP）和细菌菌斑（BP）的存在。CAL 和 BOP 在病例组的评分高于对照组。病例组分别为 3.16 ± 2.43 mm 和 0.33 ± 0.24 %，对照组分别为 1.99 ± 2.23 mm 和 0.25 ± 0.24 %（p < 0.05）。两组的 BP 评分均较高（病例组：97.1 %；对照组：98.6 %，p = 1.0000）。CAP 患者中慢性牙周炎（CP）更为常见（病例组：61.4 %；对照组：41.4 %）。中重度 CP 的存在增加了 CAP 的风险[比值比（OR）= 4.4，95 %置信区间（CI）= 1.4-13.8]，即使在调整年龄、种族、性别和吸烟状况后也是如此。本研究表明，中重度慢性牙周炎与 CAP 相关。
