Ramalingam Veena V, Mani Monika, Sundaresan Vijayanand C, Karunaiya Ramesh J, Sachithanandham Jaiprasath, Kannangai Rajesh
Department of Clinical Virology, Christian Medical College, Vellore, India.
Clin Vaccine Immunol. 2012 Oct;19(10):1693-6. doi: 10.1128/CVI.00246-12. Epub 2012 Aug 1.
CD4(+) T cell count estimations are subject to high variations; hence, in this study, the previous day's tested samples were included routinely as the internal quality controls. The percentages of variation of the 2-day values were analyzed for 280 observations and the mean variation for CD4(+) and CD3(+) T cell counts ranged from 5.21% to 9.66%. This method is a good internal quality control (IQC) procedure for the estimation of CD3(+) and CD4(+) T cell counts in resource-poor settings.
CD4(+) T细胞计数的估计值存在很大差异;因此,在本研究中,前一天检测的样本被常规用作内部质量控制。对280次观察结果分析了2天数值的变化百分比,CD4(+)和CD3(+) T细胞计数的平均变化范围为5.21%至9.66%。该方法是在资源匮乏环境中估计CD3(+)和CD4(+) T细胞计数的良好内部质量控制(IQC)程序。