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Grading of laboratories on CD4+ T-lymphocyte evaluations based on acceptable data boundaries defined by the measurement error.基于测量误差定义的可接受数据界限对实验室CD4 + T淋巴细胞评估进行分级。
Cytometry. 2002 Apr 15;50(2):117-26. doi: 10.1002/cyto.10069.
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Guidelines for preventing opportunistic infections among HIV-infected persons--2002. Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America.《2002年HIV感染者机会性感染预防指南》。美国公共卫生署及美国传染病学会的建议。
MMWR Recomm Rep. 2002 Jun 14;51(RR-8):1-52.
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Br J Haematol. 1999 Sep;106(4):1059-62. doi: 10.1046/j.1365-2141.1999.01632.x.
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Response of CD4 lymphocytes and clinical consequences of treatment using ddI or ddC in patients with advanced HIV infection.晚期HIV感染患者中CD4淋巴细胞的反应以及使用去羟肌苷（ddI）或双脱氧胞苷（ddC）治疗的临床后果。
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CD4+ T-lymphocyte measures in the treatment of individuals infected with human immunodeficiency virus type 1. A review for clinical practitioners.1型人类免疫缺陷病毒感染个体治疗中的CD4 + T淋巴细胞检测。临床医生综述
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印度南部一家三级护理中心通过FACSCount系统对CD3 +和CD4 + T细胞进行每日质量控制。

Daily quality control in CD3+ and CD4+ T cell estimation by the FACSCount system at a tertiary care center in south India.

作者信息

Ramalingam Veena V, Mani Monika, Sundaresan Vijayanand C, Karunaiya Ramesh J, Sachithanandham Jaiprasath, Kannangai Rajesh

机构信息

Department of Clinical Virology, Christian Medical College, Vellore, India.

出版信息

Clin Vaccine Immunol. 2012 Oct;19(10):1693-6. doi: 10.1128/CVI.00246-12. Epub 2012 Aug 1.

DOI:10.1128/CVI.00246-12
PMID:22855396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3485896/
Abstract

CD4(+) T cell count estimations are subject to high variations; hence, in this study, the previous day's tested samples were included routinely as the internal quality controls. The percentages of variation of the 2-day values were analyzed for 280 observations and the mean variation for CD4(+) and CD3(+) T cell counts ranged from 5.21% to 9.66%. This method is a good internal quality control (IQC) procedure for the estimation of CD3(+) and CD4(+) T cell counts in resource-poor settings.

摘要

CD4(+) T细胞计数的估计值存在很大差异；因此，在本研究中，前一天检测的样本被常规用作内部质量控制。对280次观察结果分析了2天数值的变化百分比，CD4(+)和CD3(+) T细胞计数的平均变化范围为5.21%至9.66%。该方法是在资源匮乏环境中估计CD3(+)和CD4(+) T细胞计数的良好内部质量控制（IQC）程序。