尽管使用拉米夫定进行预防，在治疗非霍奇金淋巴瘤的患者中仍发生隐匿性乙型肝炎病毒感染的短暂再激活。
Transient reactivation of occult hepatitis B virus infection despite lamivudine prophylaxis in a patient treated for non-Hodgkin lymphoma.
机构信息
Department of Public Medicine, Section of Infectious Diseases, Second University of Naples, Via L. Armanni 5, 80131, Naples, Italy.
出版信息
Infection. 2013 Feb;41(1):225-9. doi: 10.1007/s15010-012-0305-y. Epub 2012 Aug 2.
PMID:22855434
Abstract
A female patient with non-Hodgkin lymphoma who tested positive for surface antigen of the hepatitis B virus and negative for hepatitis B core antibody experienced a reactivation of occult HBV infection 20 months after rituximab discontinuation despite lamivudine prophylaxis covering the 4 months of rituximab administration and the subsequent 12 months.
摘要
一位患有非霍奇金淋巴瘤的女性患者，乙肝病毒表面抗原阳性，乙肝核心抗体阴性，在利妥昔单抗停药后 20 个月发生隐匿性乙型肝炎病毒再激活，尽管在利妥昔单抗治疗的 4 个月和随后的 12 个月中进行了拉米夫定预防。
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