University of Groningen, Department Pharmaceutical Technology and Biopharmacy, Groningen, The Netherlands.
J Aerosol Med Pulm Drug Deliv. 2012 Oct;25(5):249-60. doi: 10.1089/jamp.2011.0931. Epub 2012 Aug 2.
Pulmonary vaccine delivery has gained increasing attention during the last decade because this vaccination method combines potential advantages such as the fact that it omits the use of needles and may elicit immunity at the port of entry for many pathogens. In this review the current status of pulmonary vaccination, the potential advantages of pulmonary vaccine delivery, the hurdles to overcome in the future, and the overall perspectives of this vaccination strategy are described.
在过去的十年中，肺部疫苗输送引起了越来越多的关注，因为这种疫苗接种方法结合了一些潜在的优势，例如它避免了使用针具，并且可以在许多病原体的入侵部位引发免疫。在这篇综述中，描述了肺部疫苗接种的现状、肺部疫苗输送的潜在优势、未来需要克服的障碍以及这种疫苗接种策略的总体前景。
