Omega Medical Associates, 2 Lansing Square, Suite 304, Toronto, ON, Canada.
Can Fam Physician. 2012 Jul;58(7):740-5, e372-8.
To assess the diagnostic accuracy and clinical utility of dermoscopy for melanoma detection in family practice.
Ovid MEDLINE (1946 to June 2011), EMBASE, PubMed, and Cochrane databases were searched using the following terms: dermoscopy, dermatoscopy, epiluminescence microscopy, family practice, general practice, primary health care, melanoma, skin neoplasms, and pigmented nevus. To be included, studies had to be primary research articles with family physicians as the subjects and dermoscopy training and use as the intervention. Four papers met all inclusion criteria and provided level I evidence according to the Canadian Task Force on Preventive Health Care definition.
Among family physicians, dermoscopy has higher sensitivity for melanoma detection than naked-eye examination with generally no decrease in specificity. Dermoscopy also helps to increase family physicians' confidence in their preliminary diagnosis of lesions. When using dermoscopy, compared with naked-eye examination, there is a higher likelihood that a lesion assessed as being malignant is in fact malignant and that a lesion assessed as being benign is in fact benign.
Dermoscopy has been shown to be a useful and fairly inexpensive tool for melanoma detection in family practice. This technique can increase family physicians' confidence in their referral accuracy to dermatologists and can assist in decreasing unnecessary biopsies. Dermoscopy might be especially useful in examining patients at high risk of melanoma, as the current Canadian clinical practice guideline recommends yearly screening in these individuals.
评估家庭医生皮肤科临床检查在黑色素瘤诊断中的准确性和临床实用性。
采用以下术语对 Ovid MEDLINE(1946 年至 2011 年 6 月)、EMBASE、PubMed 和 Cochrane 数据库进行检索:皮肤科临床检查、皮肤镜检、表皮透光显微镜检查、家庭医学、一般实践、初级卫生保健、黑色素瘤、皮肤肿瘤和色素痣。符合纳入标准的研究必须为以家庭医生为研究对象,以皮肤科临床检查培训和使用为干预手段的原始研究文章。有 4 篇论文符合所有纳入标准,并根据加拿大预防保健工作组的定义提供了一级证据。
在家庭医生中,与肉眼检查相比,皮肤科临床检查对黑色素瘤的检测具有更高的敏感性,而特异性通常没有降低。皮肤科临床检查还可以帮助提高家庭医生对初步诊断病变的信心。使用皮肤科临床检查时,与肉眼检查相比,评估为恶性的病变实际上更有可能是恶性的,评估为良性的病变实际上更有可能是良性的。
皮肤科临床检查已被证明是家庭医生在黑色素瘤检测中一种有用且相对廉价的工具。该技术可以提高家庭医生向皮肤科医生转诊的准确性,并有助于减少不必要的活检。皮肤科临床检查可能特别适用于检查有黑色素瘤高风险的患者,因为目前加拿大的临床实践指南建议这些患者每年进行筛查。