[从蜂斗菜的根茎和齿叶橐吾的根中分离得到的新倍半萜类化合物]

[New sesquiterpenoids from the rhizomes of Petasites japonicus MAXIM. and the roots of Ligularia dentata HARA].

作者信息

Yaoita Yasunori

机构信息

Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Sendai, Japan.

出版信息

Yakugaku Zasshi. 2012;132(8):887-93. doi: 10.1248/yakushi.132.887.

DOI:10.1248/yakushi.132.887

PMID:22864346

Abstract

Over the past twenty years, our research group has been involved in the phytochemical study of terpenoids from Compositae plants. From seven species, namely, Erigeron annuus (L.) PERS., Erigeron philadelphicus L., Erigeron sumatrensis RETZ., Ligularia dentata HARA, Ligularia stenocephala MATSUM. et KOIDZ., Petasites japonicus MAXIM., and Tussilago farfara L., we isolated 83 new compounds. In this review, structural features of 19 eremophilane-type sesquiterpenoids from rhizomes of P. japonicus and 9 bisabolane-type sesquiterpenoids from roots of L. dentata are discussed.

摘要

在过去二十年里，我们的研究团队一直致力于菊科植物萜类化合物的植物化学研究。我们从七种植物中分离出了83种新化合物，这七种植物分别是一年蓬（Erigeron annuus (L.) PERS.）、费城飞蓬（Erigeron philadelphicus L.）、苏门白酒草（Erigeron sumatrensis RETZ.）、齿叶橐吾（Ligularia dentata HARA）、窄头橐吾（Ligularia stenocephala MATSUM. et KOIDZ.）、蜂斗菜（Petasites japonicus MAXIM.）和款冬（Tussilago farfara L.）。在这篇综述中，我们讨论了来自蜂斗菜根茎的19种紫穗槐烷型倍半萜和来自齿叶橐吾根的9种甜没药烷型倍半萜的结构特征。