Nagaoka S, Tani K, Ishigatsubo Y, Chiba J, Kato K, Matsunaga K, Narita M, Igarashi T, Okubo T
First Department of Internal Medicine, Yokohama City University, School of Medicine.
Kansenshogaku Zasshi. 1990 Nov;64(11):1394-9. doi: 10.11150/kansenshogakuzasshi1970.64.1394.
Twenty-two patients with polymyositis and dermatomyositis (PM-DM) were retrospectively studied with regard to development of herpes zoster. Herpes zoster occurred with high frequency in patients with PM-DM. The clinical courses of zoster infections were uneventful; no severe complications nor deaths occurred, and only one patient had post-therapeutic neuralgia. No specific therapy for this infection was necessary. Zoster tended to occur in the inactive stage of PM-DM. PM-DM patients with herpes zoster had a significantly higher incidence of antinuclear antibody. There seemed to be no relationship between steroid therapy and herpes zoster infection.
对22例多发性肌炎和皮肌炎（PM-DM）患者发生带状疱疹的情况进行了回顾性研究。带状疱疹在PM-DM患者中高发。带状疱疹感染的临床过程平稳；未发生严重并发症及死亡，仅有1例患者出现治疗后神经痛。对此感染无需特殊治疗。带状疱疹倾向于在PM-DM的非活动期发生。患有带状疱疹的PM-DM患者抗核抗体的发生率显著更高。类固醇治疗与带状疱疹感染之间似乎没有关系。
