Taylor T, Smith A N, Fulton M
Gastrointestinal Unit, University of Edinburgh, Western General Hospital, UK.
Int J Colorectal Dis. 1990 Dec;5(4):228-31. doi: 10.1007/BF00303282.
A case control study compared the bowel habit of 91 post-hysterectomy women with paired controls from the same family doctor practice. More cases had an abnormal bowel frequency, a firmer stool consistency and assessed themselves as having abnormal bowel function, predominantly constipation after hysterectomy, than controls. Significantly more cases than controls had consulted a doctor because of constipation but there was no significant difference in laxative usage. There was a significant short-term association between decreased bowel frequency and increased urinary frequency after hysterectomy. This became highly significant in those patients who developed chronic symptoms. Oophorectomy, unilateral or bilateral, did not significantly affect bowel habit other than to intensify the change in stool consistency. The hypothesis is discussed that the post-hysterectomy effects on bowel and bladder function may have a common aetiology in a degree of autonomic denervation of both viscera.
一项病例对照研究比较了91名子宫切除术后女性的排便习惯,并与来自同一家家庭医生诊所的配对对照者进行了对比。与对照组相比,更多的病例出现排便频率异常、大便质地更硬,且自我评估为肠道功能异常,主要是子宫切除术后便秘。因便秘而咨询医生的病例明显多于对照组,但泻药使用情况无显著差异。子宫切除术后排便频率降低与尿频增加之间存在显著的短期关联。在出现慢性症状的患者中,这种关联变得极为显著。单侧或双侧卵巢切除术除了加剧大便质地的变化外,对排便习惯没有显著影响。文中讨论了这样一种假说,即子宫切除术后对肠道和膀胱功能的影响可能在一定程度上源于两个内脏器官的自主神经去神经支配这一共同病因。