Department of Pediatrics, Gelre Hospitals, Postbus 9014, 7300 DS Apeldoorn, The Netherlands.
Eur J Pediatr. 2012 Nov;171(11):1687-93. doi: 10.1007/s00431-012-1806-5. Epub 2012 Aug 9.
Obesity is increasing worldwide and it is accompanied by major health effects. In adults and school-aged children, obesity is associated with decreased respiratory function, which may lead to disturbed sleeping and subsequently difficulties in concentration and behavioural disorders. The evidence for the association between obesity and decreased respiratory function in younger children is scarce. To explore the association between body weight and nocturnal respiratory function in young children, 1 to 3 years old, nocturnal pulse oximetry was performed at home. Children with tonsillar hypertrophy were excluded. Percentage of time with oxygen saturation (SpO(2)) <95 % was measured and its association with body mass index (BMI) for age z scores was analysed. Pulse oximetric data of 51 children, including 18 children with a BMI for age above +2 standard deviations, were obtained for this study. Linear regression analysis, correction for gender and parental smoking, showed a positive association between the natural logarithm of SpO(2) <95 % and BMI for age z score [regression coefficient (β) 0.19, 95 % confidence interval 0.00-0.39].
In young children, higher body weight is associated with a decrease in nocturnal oxygen saturation.
肥胖症在全球范围内不断增加，伴随着许多健康问题。在成年人和学龄儿童中，肥胖与呼吸功能下降有关，这可能导致睡眠障碍，进而导致注意力不集中和行为障碍。肥胖与幼儿呼吸功能下降之间的关联证据有限。为了探究 1 至 3 岁幼儿体重与夜间呼吸功能之间的关系，在家中进行了夜间脉搏血氧饱和度监测。排除扁桃体肥大的儿童。测量血氧饱和度（SpO2）<95%的时间百分比，并分析其与体重指数（BMI）的关系。本研究共获得 51 名儿童的脉搏血氧计数据，其中 18 名儿童 BMI 超过+2 个标准差。线性回归分析，校正性别和父母吸烟因素后，显示 SpO2<95%的自然对数值与 BMI 年龄 z 评分呈正相关[回归系数（β）0.19，95%置信区间 0.00-0.39]。
在幼儿中，体重越高与夜间血氧饱和度下降有关。
