Butcher Martyn
Br J Nurs. 2012;21(12):S16, S18-21. doi: 10.12968/bjon.2012.21.Sup12.S16.
The effective management of bacterial bioburden is an essential element of wound care. Recent years have seen the increased use of topical antimicrobial dressings to control colonisation and infection, yet there is concern that some may inhibit wound healing and may have systemic sequelae (World Union of Wound Healing Societies (WUWHS), 2008). This article focuses on the safety and effectiveness of PHMB, an antimicrobial compound that is relatively underused in the UK, and argues that it is an effective option for the management of bacterial colonisation and infection.
有效管理细菌生物负载是伤口护理的重要环节。近年来,局部抗菌敷料用于控制定植和感染的情况日益增多,但有人担心某些敷料可能会抑制伤口愈合并产生全身后遗症(世界伤口愈合协会联盟(WUWHS),2008年)。本文重点关注聚六亚甲基双胍(PHMB)的安全性和有效性,这种抗菌化合物在英国的使用相对较少,并认为它是管理细菌定植和感染的有效选择。