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质谱和生物分析技术在环境样品中新兴有机污染物分析方面的成就和未来趋势。

Achievements and future trends in the analysis of emerging organic contaminants in environmental samples by mass spectrometry and bioanalytical techniques.

机构信息

Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), C/Jordi Girona, 18-26, 08911 Barcelona, Spain.

出版信息

J Chromatogr A. 2012 Oct 12;1259:86-99. doi: 10.1016/j.chroma.2012.07.024. Epub 2012 Jul 20.

DOI:10.1016/j.chroma.2012.07.024
PMID:22877973
Abstract

Several groups of organic compounds have emerged as particularly relevant as environmental pollutants. These compounds, including new brominated flame retardants, disinfection by-products, drugs of abuse and their metabolites, hormones and other endocrine disrupting compounds, nanomaterials, perfluoroalkyl substances, pharmaceuticals and siloxanes among others, constitute new risks for environmental and human health. In order to face up to these new risk challenges there is an increasing need to assess their occurrence and behaviour in the environment, as well as, that of their degradation products. Therefore, during recent years an important part of research has been focused on to the improvement of analytical schemes for complex matrices, in which the new tendencies in sample preparation (e.g. online clean up systems), the development of new materials and new mass spectrometry analysers have played an important role. This paper presents a general overview of new analytical trends and potentials in trace analysis of emerging pollutants in the environment, including chromatographic techniques coupled to mass spectrometry, and bio analytical approaches (biosensors).

摘要

已经有几类有机化合物作为环境污染物,显得尤为重要。这些化合物包括新型溴化阻燃剂、消毒副产物、滥用药物及其代谢物、激素和其他内分泌干扰物、纳米材料、全氟烷基物质、药品和硅氧烷等,它们对环境和人类健康构成了新的风险。为了应对这些新的风险挑战,人们越来越需要评估它们在环境中的存在和行为,以及它们的降解产物。因此,近年来,研究的一个重要部分集中在改进复杂基质的分析方案上,其中样品制备的新趋势(例如在线净化系统)、新材料和新型质谱分析仪的发展发挥了重要作用。本文对环境中新兴污染物痕量分析的新分析趋势和潜力进行了综述,包括与质谱联用的色谱技术和生物分析方法(生物传感器)。

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