Dept. of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC), Jordi Girona 18-26, E-08034 Barcelona, Spain.
J Chromatogr A. 2010 Jun 18;1217(25):4004-17. doi: 10.1016/j.chroma.2010.02.059. Epub 2010 Mar 3.
An overview of liquid chromatography-mass spectrometry methods used for the determination of trace organic contaminants in environmental samples is presented. Among the organic contaminants the focus is given on five groups of emerging contaminants that raised most concern as environmental contaminants and therefore attracted attention of a research community: pharmaceuticals, drugs of abuse, polar pesticides, perfluorinated compounds and nanoparticles. Various aspects of current LC-MS methodology, using tandem and hybrid MS instruments, including sample preparation, are discussed.
介绍了用于测定环境样品中痕量有机污染物的液相色谱-质谱联用方法。在这些有机污染物中,重点介绍了引起人们对环境污染物最关注的五类新兴污染物,因此引起了研究界的关注:药物、滥用药物、极性农药、全氟化合物和纳米颗粒。讨论了当前使用串联和混合 MS 仪器的 LC-MS 方法的各个方面,包括样品制备。