Department of Entomology, University of Kentucky, Lexington, KY 40546, USA.
Pest Manag Sci. 2013 Feb;69(2):240-4. doi: 10.1002/ps.3376. Epub 2012 Aug 8.
Bed bugs (Cimex lectularius L.) have become a common insect pest in urban areas and are often difficult to manage. Eradication is made more problematic by widespread insecticide resistance, raising interest in alternative control products. Juvenile hormone analogs (JHAs) such as methoprene and hydroprene are relatively harmless to non-arthropods and have proved to be effective against other urban insect pests. Two JHA products (Gentrol(®) and Precor(®), Central Life Sciences, Schaumburg, IL) were tested for efficacy against various bed bug stages as direct spray and as dry residue using three bed bug strains.
At 1× and 2× the label rate, Precor(®) [active ingredient (S)-methoprene] had no significant effect on the development or fecundity of bed bugs. At 2× the label rate, confinement to residues of Gentrol(®) [active ingredient (S)-hydroprene] had no significant effect, but residues at 3× and 10× the label rate caused a reduction in fecundity and impaired development. Field strains were more susceptible to the reproductive effects of (S)-hydroprene than a long-maintained laboratory strain.
While JHAs are attractive alternatives for pest management because of their inherent safety and distinct mode of action, these JHA formulations would have little impact on bed bug populations without relabeling to allow for higher application rates.
臭虫（Cimex lectularius L.）已成为城市地区常见的昆虫害虫，通常难以管理。由于广泛的杀虫剂抗性，根除变得更加困难，这引起了人们对替代控制产品的兴趣。保幼激素类似物（JHAs），如灭幼脲和双氧威，对非节肢动物相对无害，并已被证明对其他城市害虫有效。两种 JHA 产品（Gentrol（®）和 Precor（®），Central Life Sciences，Schaumburg，IL）已被测试用于直接喷雾和作为干残余物对各种臭虫阶段的功效，使用了三种臭虫品系。
在 1×和 2×标签率下，Precor（®）[有效成分（S）-灭幼脲]对臭虫的发育或繁殖没有显著影响。在 2×标签率下，将 Gentrol（®）[有效成分（S）-双氧威]限制在残留物中没有显著影响，但残留物在 3×和 10×标签率下会降低繁殖力并损害发育。田间品系比长期维持的实验室品系对（S）-双氧威的生殖影响更为敏感。
虽然 JHAs 因其固有的安全性和独特的作用模式而成为害虫管理的有吸引力的替代品，但这些 JHA 制剂如果不重新标记以允许更高的应用率，对臭虫种群的影响将很小。
