Campbell Brittany, Baldwin Rebecca, Koehler Philip
Department of Entomology and Nematology, University of Florida, Gainesville, FL 32611, USA.
Insects. 2017 Sep 1;8(3):94. doi: 10.3390/insects8030094.
To date, few studies have evaluated chitin synthesis inhibitors against bed bugs, although they would provide an alternative mode of action to circumvent insecticide resistance. Acute and sublethal effects of lufenuron were evaluated against two strains of the common bed bug. Combined acute and sublethal effects were used to calculate effective doses. The dose that was effective against 50% of Harlan strain bed bugs was 0.0081% (/), and was much higher against Bradenton strain bed bugs (1.11% /). Sublethal doses were chosen to determine the effect that leg abnormalities had on pulling force. Both Harlan and Bradenton strain bed bugs had significantly lower locomotion ability ( < 0.0001) following topical application of lufenuron. The observed sublethal effects that limit locomotion could prevent bed bugs from moving within a domicile and taking a blood meal, subsequently reducing a bed bug population over time.
迄今为止，很少有研究评估几丁质合成抑制剂对臭虫的作用，尽管它们将提供一种替代作用模式来规避杀虫剂抗性。评估了虱螨脲对两种常见臭虫品系的急性和亚致死效应。综合急性和亚致死效应来计算有效剂量。对50%的哈伦品系臭虫有效的剂量为0.0081%（/），而对布雷登顿品系臭虫的有效剂量则高得多（1.11% /）。选择亚致死剂量来确定腿部异常对拉力的影响。在局部施用虱螨脲后，哈伦品系和布雷登顿品系臭虫的运动能力均显著降低（<0.0001）。观察到的限制运动的亚致死效应可能会阻止臭虫在住所内移动并取食血液，从而随着时间的推移减少臭虫数量。
