Faculty of Medicine, Urology and Nephrology Clinic, Clinical Centre of Montenegro, University of Montenegro, 20000Podgorica, Montenegro.
Andrologia. 2013 Aug;45(4):266-71. doi: 10.1111/and.12004. Epub 2012 Aug 16.
Pyospermia is the abnormally high concentration of white blood cells in human ejaculate, as caused by a bacterial infection. This study addresses the evaluation of the use of an antibiotic treatment in infertile patients who show asymptomatic pyospermia through the monitoring of semen analysis parameters. The study was carried out on 60 infertile patients who were diagnosed with asymptomatic genital infections, focused on pyospermia caused by Chlamydia trachomatis and Ureaplasma urealyticum. The volume of the ejaculate, pH, sperm concentration and progressive motility, as well as the viability of the spermatozoa and their morphology, were all observed before therapy, 10 and 30 days after. Patients were treated with antibiotics in accordance with the recommendations given by the European Urology Association. The results showed a clear effect of antibiotic therapy on the volume and pH of the seminal fluid; moreover, only 30 days after completion of the therapy sperm concentration itself significantly increased, and progressive motility greatly improved, albeit slowly. However, it must be noted that the antibiotic therapy had no significant effect on the viability of the spermatozoa within 30 days of beginning the treatment.
精浆白细胞增多症是指人类精液中白细胞异常增高，通常由细菌感染引起。本研究旨在评估在无症状精浆白细胞增多症的不育患者中使用抗生素治疗的效果，通过监测精液分析参数来进行评估。本研究共纳入 60 例诊断为无症状生殖器感染的不育患者，主要针对沙眼衣原体和解脲支原体引起的精浆白细胞增多症。在治疗前、治疗后 10 天和 30 天分别观察精液量、pH 值、精子浓度和前向运动精子比例，以及精子活力和形态。根据欧洲泌尿外科学会的建议，患者接受了抗生素治疗。结果表明，抗生素治疗对精液量和 pH 值有明显影响；此外，仅在治疗完成后 30 天，精子浓度本身就显著增加，前向运动精子比例显著改善，尽管改善速度较慢。然而，必须注意的是，抗生素治疗在治疗开始后 30 天内对精子活力没有显著影响。
