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一例罕见的小儿神经型布鲁氏菌病合并颅内高压病例。

An uncommon case of pediatric neurobrucellosis associated with intracranial hypertension.

作者信息

Sinopidis Xenophon, Kaleyias Joseph, Mitropoulou Konstantina, Triga Maria, Kothare Sanjeev V, Mantagos Stefanos

机构信息

Department of Pediatric Surgery, Patras University Hospital, University of Patras Medical School, Patras 26504, Greece.

出版信息

Case Rep Infect Dis. 2012;2012:492467. doi: 10.1155/2012/492467. Epub 2012 Jul 29.

Abstract

We present the case of a 4-year-old boy who was admitted to hospital with intracranial hypertension, headache, diplopia, papilledema, and a normal brain MRI. Brucella melitensis in the cerebrospinal fluid was confirmed with PCR assay. We believe that neurobrucellosis should be included in the differential diagnosis when headaches persist following brucellosis. In addition, we suggest that when cerebrospinal fluid culture is negative, PCR may prove to be an optimal alternative tool for an immediate and accurate diagnosis.

摘要

我们报告了一名4岁男孩的病例,该男孩因颅内高压、头痛、复视、视乳头水肿入院,脑部MRI检查正常。通过PCR检测确诊脑脊液中有羊种布鲁氏菌。我们认为,当布鲁氏菌病后头痛持续时,应将神经型布鲁氏菌病纳入鉴别诊断。此外,我们建议,当脑脊液培养结果为阴性时,PCR可能是一种即时准确诊断的最佳替代工具。

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A rare case of seronegative neurobrucellosis.一例罕见的血清阴性神经型布鲁氏菌病病例。
Ann Saudi Med. 2010 Sep-Oct;30(5):412-4. doi: 10.4103/0256-4947.67084.

本文引用的文献

1
Neurobrucellosis.神经布鲁菌病。
Neuroimaging Clin N Am. 2011 Nov;21(4):927-37, ix. doi: 10.1016/j.nic.2011.07.008.
4
Idiopathic intracranial hypertension presenting as unilateral papilledema.
Neurol India. 2010 Sep-Oct;58(5):818-9. doi: 10.4103/0028-3886.72208.
5
Overview of neurobrucellosis: a pooled analysis of 187 cases.神经型布鲁菌病概述:187 例汇总分析。
Int J Infect Dis. 2009 Nov;13(6):e339-43. doi: 10.1016/j.ijid.2009.02.015. Epub 2009 May 9.
7
Neurobrucellosis in the UK.英国的神经型布鲁氏菌病。
J Infect. 2009 Jan;58(1):88-9. doi: 10.1016/j.jinf.2008.11.006. Epub 2008 Dec 10.

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