Katosova R K, Amanmuradov A Kh, Podoprigora G I, Akinshina G T, Sabgaĭda T P
Med Parazitol (Mosk). 1990 Nov-Dec(6):17-9.
Succinic dehydrogenase (SDH) activity in peripheral blood lymphocytes has been studied in progressing experimental malaria on a P. yoelii model, the strain 265 BY; the multinipple rats Mastomys natalensis. Cytochemical method employing n-nitrotetrazolium violet was used. Comparative analysis of changes in SDG activity in peripheral blood lymphocytes and changes in the level of parasitemia has demonstrated that day 10 was a critical period when there was an evident inverse correlation between the qualitative parameters. The findings give evidence of SDH participation in an adequate response of immunocompetent cells to malaria infection, thus leading to recovery.
在约氏疟原虫265BY株感染多乳突大鼠马斯托鼠的进行性实验性疟疾模型中，研究了外周血淋巴细胞中的琥珀酸脱氢酶（SDH）活性。采用了使用硝基四氮唑蓝的细胞化学方法。对外周血淋巴细胞中SDG活性变化与疟原虫血症水平变化的比较分析表明，第10天是一个关键时期，此时定性参数之间存在明显的负相关。这些发现证明SDH参与了免疫活性细胞对疟疾感染的适当反应，从而导致恢复。
