平行微流光化学：过程优化、放大和文库合成。
Parallel microflow photochemistry: process optimization, scale-up, and library synthesis.
机构信息
Dublin City University, School of Chemical Sciences, Dublin 9, Ireland.
出版信息
Org Lett. 2012 Sep 7;14(17):4342-5. doi: 10.1021/ol301773r. Epub 2012 Aug 20.
PMID:22905680
Abstract
A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.
摘要
构建了一种新型的多微流控反应器（MμCFR），并将其应用于一系列涉及 2(5H)-呋喃酮的敏化光加成反应。该反应器可实现快速、节能、省时和节省空间的敏化剂筛选、工艺优化、验证、放大和文库合成。
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