Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University , 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
J Org Chem. 2014 May 2;79(9):3838-46. doi: 10.1021/jo500190b. Epub 2014 Apr 16.
We have developed an automated photochemical microfluidics platform that integrates a 1 kW high-pressure Hg vapor lamp and allows for analytical pulse flow or preparative continuous flow reactions. Herein, we will discuss the use of this platform toward the discovery of new chemotypes through multidimensional reaction screening. We will highlight the ability to discretely control wavelengths with optical filters, allowing for control of reaction outcomes.
我们开发了一种自动化光化学微流控平台，它集成了 1kW 高压汞蒸气灯，并允许进行分析脉冲流或制备连续流反应。在此，我们将讨论通过多维反应筛选来利用该平台发现新化学型的情况。我们将重点介绍使用光学滤波器离散控制波长的能力，从而控制反应结果。
