Institute of Sound and Vibration Research, University of Southampton, Southampton, Hampshire, SO17 1BJ, UK.
Biomech Model Mechanobiol. 2013 Jun;12(3):581-96. doi: 10.1007/s10237-012-0427-2. Epub 2012 Aug 21.
The isometric force response of the locust hind leg extensor tibia muscle to stimulation of a slow extensor tibia motor neuron is experimentally investigated, and a mathematical model describing the response presented. The measured force response was modelled by considering the ability of an existing model, developed to describe the response to the stimulation of a fast extensor tibia motor neuron and to also model the response to slow motor neuron stimulation. It is found that despite large differences in the force response to slow and fast motor neuron stimulation, which could be accounted for by the differing physiology of the fibres they innervate, the model is able to describe the response to both fast and slow motor neuron stimulation. Thus, the presented model provides a potentially generally applicable, robust, simple model to describe the isometric force response of a range of muscles.
实验研究了蝗虫后肢伸肌胫骨肌对慢伸肌胫骨运动神经元刺激的等长力反应，并提出了描述该反应的数学模型。通过考虑现有模型的能力，对测量得到的力反应进行建模，该模型用于描述对快速伸肌胫骨运动神经元刺激的反应，并进一步对慢运动神经元刺激的反应进行建模。研究发现，尽管慢运动神经元和快运动神经元刺激的力反应存在很大差异，这可以用它们所支配的纤维的不同生理学来解释，但该模型能够描述对快运动神经元和慢运动神经元刺激的反应。因此，所提出的模型提供了一个潜在的通用、鲁棒、简单的模型，用于描述一系列肌肉的等长力反应。
