在利福昔明治疗期间体内筛选利福霉素耐药艰难梭菌。
In vivo selection of rifamycin-resistant Clostridium difficile during rifaximin therapy.
机构信息
TechLab, Inc., Blacksburg, Virginia, USA.
出版信息
Antimicrob Agents Chemother. 2012 Nov;56(11):6019-20. doi: 10.1128/AAC.00974-12. Epub 2012 Aug 20.
Abstract
We report the selection of Clostridium difficile resistant to the rifamycin class of antibiotics in a patient within 32 h of receiving rifaximin for the treatment of recurrent C. difficile diarrhea. Resistance was associated with single nucleotide substitutions within rpoB.
摘要
我们报道了一名患者在接受利福昔明治疗复发性艰难梭菌腹泻后 32 小时内对利福霉素类抗生素耐药的艰难梭菌的选择。耐药性与 rpoB 内的单核苷酸取代有关。
相似文献
1
In vivo selection of rifamycin-resistant Clostridium difficile during rifaximin therapy.在利福昔明治疗期间体内筛选利福霉素耐药艰难梭菌。
Antimicrob Agents Chemother. 2012 Nov;56(11):6019-20. doi: 10.1128/AAC.00974-12. Epub 2012 Aug 20.
2
Rifampin and rifaximin resistance in clinical isolates of Clostridium difficile.艰难梭菌临床分离株中的利福平及利福昔明耐药性
Antimicrob Agents Chemother. 2008 Aug;52(8):2813-7. doi: 10.1128/AAC.00342-08. Epub 2008 Jun 16.
3
Use of rifamycin drugs and development of infection by rifamycin-resistant strains of Clostridium difficile.利福霉素类药物的使用与难辨梭状芽孢杆菌利福霉素耐药株感染的发展。
Antimicrob Agents Chemother. 2013 Jun;57(6):2690-3. doi: 10.1128/AAC.00548-13. Epub 2013 Apr 1.
4
Rifamycin Resistance in Clostridium difficile Is Generally Associated with a Low Fitness Burden.艰难梭菌中的利福平耐药性通常与较低的适应性负担相关。
Antimicrob Agents Chemother. 2016 Aug 22;60(9):5604-7. doi: 10.1128/AAC.01137-16. Print 2016 Sep.
5
Divergent rifamycin susceptibilities of Clostridium difficile strains in Canada and Italy and predictive accuracy of rifampin Etest for rifamycin resistance.加拿大和意大利艰难梭菌菌株对利福霉素的不同敏感性及利福平 Etest 预测利福霉素耐药性的准确性。
J Clin Microbiol. 2011 Dec;49(12):4319-21. doi: 10.1128/JCM.05100-11. Epub 2011 Oct 12.
6
In vivo selection of moxifloxacin-resistant Clostridium difficile.体内筛选耐莫西沙星的艰难梭菌
Antimicrob Agents Chemother. 2012 May;56(5):2788-9. doi: 10.1128/AAC.06433-11. Epub 2012 Feb 27.
7
High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital.在一家大型教学医院的一株流行艰难梭菌克隆株中发现利福平耐药的高频率。
Clin Infect Dis. 2009 Feb 15;48(4):425-9. doi: 10.1086/596315.
8
Rifamycin antibiotics for treatment of Clostridium difficile-associated diarrhea.利福霉素类抗生素用于治疗艰难梭菌相关性腹泻。
Ann Pharmacother. 2008 Jun;42(6):827-35. doi: 10.1345/aph.1K675. Epub 2008 Apr 22.
9
Fluoroquinolone resistance and Clostridium difficile, Germany.氟喹诺酮类药物耐药与艰难梭菌，德国。
Emerg Infect Dis. 2010 Apr;16(4):675-7. doi: 10.3201/eid1604.090859.
10
In vitro activity and single-step mutational analysis of rifamycin SV tested against enteropathogens associated with traveler's diarrhea and Clostridium difficile.检测 rifamycin SV 对旅行者腹泻和艰难梭菌相关病原体的体外活性和单步突变分析。
Antimicrob Agents Chemother. 2011 Mar;55(3):992-6. doi: 10.1128/AAC.00688-10. Epub 2010 Dec 13.
引用本文的文献
1
Infection: Diagnosis and Treatment Challenges.感染：诊断与治疗挑战
Pathogens. 2024 Jan 27;13(2):118. doi: 10.3390/pathogens13020118.
2
Antibiotic Resistances of Clostridioides difficile.艰难梭菌的抗生素耐药性。
Adv Exp Med Biol. 2024;1435:169-198. doi: 10.1007/978-3-031-42108-2_9.
3
Mechanisms and impact of antimicrobial resistance in Clostridioides difficile.艰难梭菌中抗菌药物耐药性的机制及影响
Curr Opin Microbiol. 2022 Apr;66:63-72. doi: 10.1016/j.mib.2022.01.004. Epub 2022 Jan 22.
4
Antimicrobial resistance in Clostridioides difficile.艰难梭菌中的抗菌药物耐药性。
Eur J Clin Microbiol Infect Dis. 2021 Dec;40(12):2459-2478. doi: 10.1007/s10096-021-04311-5. Epub 2021 Aug 24.
5
Evaluation of the antimicrobial activity of ridinilazole and six comparators against Chinese, Japanese and South Korean strains of Clostridioides difficile.评估利奈唑胺和六种对照药物对来自中、日、韩的艰难梭菌菌株的抗菌活性。
J Antimicrob Chemother. 2021 Mar 12;76(4):967-972. doi: 10.1093/jac/dkaa522.
6
Antimicrobial Susceptibilities of Clostridium difficile Isolates from 12 Asia-Pacific Countries in 2014 and 2015.2014 年和 2015 年来自亚太地区 12 个国家的艰难梭菌分离株的抗菌药敏性。
Antimicrob Agents Chemother. 2020 Jun 23;64(7). doi: 10.1128/AAC.00296-20.
7
Recommendations for the diagnosis and treatment of Clostridioides difficile infection: An official clinical practice guideline of the Spanish Society of Chemotherapy (SEQ), Spanish Society of Internal Medicine (SEMI) and the working group of Postoperative Infection of the Spanish Society of Anesthesia and Reanimation (SEDAR).艰难梭菌感染的诊断和治疗建议：西班牙化疗学会（SEQ）、西班牙内科学会（SEMI）和西班牙麻醉与复苏学会术后感染工作组（SEDAR）的官方临床实践指南。
Rev Esp Quimioter. 2020 Apr;33(2):151-175. doi: 10.37201/req/2065.2020. Epub 2020 Feb 20.
8
An outbreak of Clostridium difficile PCR ribotype 027 in Spain: risk factors for recurrence and a novel treatment strategy.西班牙产艰难梭菌 PCR 核糖型 027 的爆发：复发的危险因素和一种新的治疗策略。
Eur J Clin Microbiol Infect Dis. 2017 Oct;36(10):1777-1786. doi: 10.1007/s10096-017-2991-y. Epub 2017 May 13.
9
Conventional and alternative treatment approaches for infection.感染的传统和替代治疗方法。
Int J Health Sci (Qassim). 2017 Jan-Mar;11(1):1-10.
10
Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders.功能性肠病中肠道微生物群的治疗性调节
J Neurogastroenterol Motil. 2017 Jan 30;23(1):9-19. doi: 10.5056/jnm16124.
本文引用的文献
1
In vivo selection of moxifloxacin-resistant Clostridium difficile.体内筛选耐莫西沙星的艰难梭菌
Antimicrob Agents Chemother. 2012 May;56(5):2788-9. doi: 10.1128/AAC.06433-11. Epub 2012 Feb 27.
2
Divergent rifamycin susceptibilities of Clostridium difficile strains in Canada and Italy and predictive accuracy of rifampin Etest for rifamycin resistance.加拿大和意大利艰难梭菌菌株对利福霉素的不同敏感性及利福平 Etest 预测利福霉素耐药性的准确性。
J Clin Microbiol. 2011 Dec;49(12):4319-21. doi: 10.1128/JCM.05100-11. Epub 2011 Oct 12.
3
A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection.一项随机、双盲、安慰剂对照的初步研究，旨在评估利福昔明预防艰难梭菌感染患者复发腹泻的能力。
J Antimicrob Chemother. 2011 Dec;66(12):2850-5. doi: 10.1093/jac/dkr377. Epub 2011 Sep 21.
4
Rifaximin Redux: treatment of recurrent Clostridium difficile infections with rifaximin immediately post-vancomycin treatment.利福昔明：万古霉素治疗后即刻应用利福昔明治疗复发性艰难梭菌感染。
Anaerobe. 2009 Dec;15(6):290-1. doi: 10.1016/j.anaerobe.2009.08.004. Epub 2009 Aug 18.
5
High frequency of rifampin resistance identified in an epidemic Clostridium difficile clone from a large teaching hospital.在一家大型教学医院的一株流行艰难梭菌克隆株中发现利福平耐药的高频率。
Clin Infect Dis. 2009 Feb 15;48(4):425-9. doi: 10.1086/596315.
6
Rifampin and rifaximin resistance in clinical isolates of Clostridium difficile.艰难梭菌临床分离株中的利福平及利福昔明耐药性
Antimicrob Agents Chemother. 2008 Aug;52(8):2813-7. doi: 10.1128/AAC.00342-08. Epub 2008 Jun 16.
7
Multiplex PCR targeting tpi (triose phosphate isomerase), tcdA (Toxin A), and tcdB (Toxin B) genes for toxigenic culture of Clostridium difficile.针对艰难梭菌产毒培养的磷酸丙糖异构酶（tpi）、毒素A（tcdA）和毒素B（tcdB）基因的多重聚合酶链反应。
J Clin Microbiol. 2004 Dec;42(12):5710-4. doi: 10.1128/JCM.42.12.5710-5714.2004.
8
PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes.针对艰难梭菌16S - 23S rRNA基因间隔区的聚合酶链反应（PCR）以及由116种不同PCR核糖体分型组成的文库构建。
J Clin Microbiol. 1999 Feb;37(2):461-3. doi: 10.1128/JCM.37.2.461-463.1999.
9
Characterization of mutations in the rpoB gene that confer rifampin resistance in Staphylococcus aureus.金黄色葡萄球菌中赋予利福平抗性的rpoB基因突变的特征分析。
Antimicrob Agents Chemother. 1998 Oct;42(10):2590-4. doi: 10.1128/AAC.42.10.2590.
Zotero 插件