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Hemcon牙科敷料与传统止血方法对40例口服抗血小板药物患者的疗效比较

Effectiveness of Hemcon Dental Dressing versus Conventional Method of Haemostasis in 40 Patients on Oral Antiplatelet Drugs.

作者信息

Kale Tejraj P, Singh Amit Kumar, Kotrashetti S M, Kapoor Abhishek

机构信息

Department of Oral and Maxillofacial Surgery, KLE Vishwanath Katti Institute of Dental Sciences, Belgaum, Karnataka, India.

出版信息

Sultan Qaboos Univ Med J. 2012 Aug;12(3):330-5. doi: 10.12816/0003147. Epub 2012 Jul 15.

DOI:10.12816/0003147
PMID:22912926
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3413624/
Abstract

OBJECTIVES

The purpose of the study was to evaluate the effectiveness of the HemCon Dental Dressing (HDD) in controlling post extraction bleeding and to ascertain its role in healing of extraction wounds, as compared to control.

METHODS

The 40 participants in the study were all receiving oral antiplatelet therapy (OAT). A total of 80 extractions were conducted without altering the patients' drug therapy. The extraction sites were divided into 2 groups: one group received a HDD, and the control group where the conventional method of pressure pack with sterile gauze under biting pressure (followed by suturing if required) was used to achieve haemostasis.

RESULTS

All HemCon treated sites achieved haemostasis sooner (mean = 53 seconds) than the control sites (mean = 918 seconds) which was statistically significant (P <0.001). Postoperative pain in the HDD group (1.74) was also significantly lower than in the control group (5.26) (P <0.001). Approximately 72.5% of HDD-treated sites showed significantly better postoperative healing when compared to the control site (P <0.001).

CONCLUSION

HDD proved to be an excellent haemostatic agent that significantly shortened the bleeding time following dental extraction in patients on OAT. Additionally, HDD offered significantly improved post-operative healing of the extraction socket and less postoperative pain.

摘要

目的

本研究旨在评估HemCon牙科敷料(HDD)在控制拔牙后出血方面的有效性,并确定其在拔牙创口愈合中的作用,与对照组进行比较。

方法

本研究的40名参与者均接受口服抗血小板治疗(OAT)。在不改变患者药物治疗的情况下,共进行了80次拔牙。拔牙部位分为2组:一组接受HDD,对照组采用传统方法,即在咬合压力下用无菌纱布进行压迫包扎(必要时缝合)以实现止血。

结果

所有接受HemCon治疗的部位止血时间均比对照组更快(平均 = 53秒,对照组平均 = 918秒),具有统计学意义(P <0.001)。HDD组的术后疼痛(1.74)也显著低于对照组(5.26)(P <0.001)。与对照部位相比,约72.5%接受HDD治疗的部位术后愈合明显更好(P <0.001)。

结论

HDD被证明是一种出色的止血剂,可显著缩短接受OAT治疗的患者拔牙后的出血时间。此外,HDD能显著改善拔牙窝的术后愈合情况,并减轻术后疼痛。

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