Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Dermatol Ther. 2012 May-Jun;25(3):273-6. doi: 10.1111/j.1529-8019.2012.01456.x.
Hypertrophic scars and keloids exhibit high recurrence rates following surgical excision. Intralesional cryosurgery (ILC) can achieve a higher degree of effectiveness than the surface cryotherapy. The aim of this study is to assess the clinical efficacy of ILC using Weshahy cryoneedles followed by IL steroid in a trial of getting rid of the fibrous mass by destruction, not by surgery to avoid being under tension of the new scar. This study included 22 patients. Evaluation of the volume reduction of the lesions was done after a single ILC session followed by IL steroid injections. There was a significant decrease in the volume of the lesions after 4 months (P < 0.01), with a volume reduction of 93.5%. By using ILC at the base of keloids or hypertrophic scars, we can change the old fibrous tissue into a recent scar or granulation tissue which will respond more successfully to IL steroid injection.
增生性瘢痕和瘢痕疙瘩在手术切除后复发率很高。瘤内冷冻疗法(ILC)比表面冷冻疗法更有效。本研究旨在评估使用 Weshahy 冷冻针进行 ILC 联合 IL 皮质类固醇治疗的临床疗效,通过破坏纤维肿块而不是手术来避免新瘢痕的张力,从而达到消除纤维肿块的目的。本研究纳入 22 例患者。在单次 ILC 治疗后行 IL 皮质类固醇注射,评估病变体积缩小情况。4 个月后,病变体积有显著下降(P<0.01),体积减少 93.5%。通过在瘢痕疙瘩或增生性瘢痕的底部使用 ILC,可以将旧的纤维组织转变为近期的瘢痕或肉芽组织,这将更成功地对 IL 皮质类固醇注射做出反应。