Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital, Honkomagome 3-18-22, Bunkyo-ku, Tokyo 113-8677, Japan.
J Radiat Res. 2012 Nov 1;53(6):999-1005. doi: 10.1093/jrr/rrs048. Epub 2012 Aug 21.
When a brass compensator is set in a treatment beam, beam hardening may take place. This variation of the energy spectrum may affect the accuracy of dose calculation by a treatment planning system and the results of dose measurement of brass compensator intensity modulated radiation therapy (IMRT). In addition, when X-rays pass the compensator, scattered photons are generated within the compensator. Scattered photons may affect the monitor unit (MU) calculation. In this study, to evaluate the variation of dose distribution by the compensator, dose distribution was measured and energy spectrum was simulated using the Monte Carlo method. To investigate the influence of beam hardening for dose measurement using an ionization chamber, the beam quality correction factor was determined. Moreover, to clarify the effect of scattered photons generated within the compensator for the MU calculation, the head scatter factor was measured and energy spectrum analyses were performed. As a result, when X-rays passed the brass compensator, beam hardening occurred and dose distribution was varied. The variation of dose distribution and energy spectrum was larger with decreasing field size. This means that energy spectrum should be reproduced correctly to obtain high accuracy of dose calculation for the compensator IMRT. On the other hand, the influence of beam hardening on k(Q) was insignificant. Furthermore, scattered photons were generated within the compensator, and scattered photons affect the head scatter factor. These results show that scattered photons must be taken into account for MU calculation for brass compensator IMRT.
当一个黄铜补偿器被设置在治疗射束中时,可能会发生射束硬化。这种能谱的变化可能会影响治疗计划系统的剂量计算准确性和对黄铜补偿器强度调制放射治疗(IMRT)的强度测量结果。此外,当 X 射线穿过补偿器时,在补偿器内会产生散射光子。散射光子可能会影响监测器单位(MU)的计算。在这项研究中,为了评估补偿器引起的剂量分布变化,使用蒙特卡罗方法测量了剂量分布并模拟了能谱。为了研究电离室剂量测量中射束硬化对剂量测量的影响,确定了束质校正因子。此外,为了阐明补偿器内产生的散射光子对 MU 计算的影响,测量了头部散射因子并进行了能谱分析。结果表明,当 X 射线穿过黄铜补偿器时,发生了射束硬化,剂量分布发生了变化。随着射野尺寸的减小,剂量分布和能谱的变化越大。这意味着为了获得补偿器 IMRT 剂量计算的高精度,应正确再现能谱。另一方面,射束硬化对 k(Q)的影响可以忽略不计。此外,在补偿器内产生了散射光子,并且散射光子会影响头部散射因子。这些结果表明,对于黄铜补偿器 IMRT 的 MU 计算,必须考虑散射光子。