Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Curr Biol. 2012 Aug 21;22(16):R648-57. doi: 10.1016/j.cub.2012.07.025.
Endogenous circadian rhythms regulate many aspects of an organism's behavior, physiology and development. These daily oscillations synchronize with the environment to generate robust rhythms, resulting in enhanced fitness and growth vigor in plants. Collective studies over the years have focused on understanding the transcription-based oscillator in Arabidopsis. Recent advances combining mechanistic data with genome-wide approaches have contributed significantly to a more comprehensive understanding of the molecular interactions within the oscillator, and with clock-controlled pathways. This review focuses on the regulatory mechanisms within the oscillator, highlighting key connections between new and existing components, and direct mechanistic links to downstream pathways that control overt rhythms in the whole plant.
内源性昼夜节律调节生物体行为、生理和发育的许多方面。这些日常波动与环境同步，产生强大的节律，从而提高植物的适应性和生长活力。多年来的集体研究集中在理解拟南芥中的基于转录的振荡器。最近将机械数据与全基因组方法相结合的进展，极大地促进了对振荡器内分子相互作用以及与时钟控制途径的更全面理解。这篇综述重点介绍了振荡器内的调节机制，突出了新组件和现有组件之间的关键联系，以及与控制整个植物显性节律的下游途径的直接机械联系。
