World J Gastroenterol. 2012 Aug 21;18(31):4241-2. doi: 10.3748/wjg.v18.i31.4241.
Intestinal bacteria play a role in the development of non-steroidal anti-inflammatory drugs (NSAID)-induced small intestinal injury. Agents such as probiotics, able to modify the gut ecology, might theoretically be useful in preventing small intestinal damage induced by NSAIDs. The clinical studies available so far do suggest that some probiotic agents can be effective in this respect.
肠道细菌在非甾体抗炎药(NSAID)诱导的小肠损伤的发展中起作用。益生菌等能够改变肠道生态的药物,理论上可能有助于预防 NSAID 引起的小肠损伤。到目前为止,现有的临床研究表明,一些益生菌制剂在这方面可能是有效的。