传染性法氏囊病病毒蛋白质的肽图比较

J Virol. 1979 Dec;32(3):1047-50. doi: 10.1128/JVI.32.3.1047-1050.1979.

The genome of infectious bursal disease virus consists of two segments of double-stranded RNA of 2.5 X 10(6) and 2.2 X 10(6) molecular weight. Polyacrylamide gel electrophoresis of purified virus resolved four structural polypeptides: VP-1 (90,000), VP-2 (41,000), VP-3 (35,000), and VP-4 (28,000). Peptide map comparisons of radioiodinated virion proteins indicated no precursor-product relationship between them. The possible relationship between the size of the virus genome and the number and sizes of different viral proteins is discussed.

传染性法氏囊病病毒的基因组由两段双链RNA组成，分子量分别为2.5×10⁶和2.2×10⁶。纯化病毒的聚丙烯酰胺凝胶电泳分离出四种结构多肽：VP-1（90,000）、VP-2（41,000）、VP-3（35,000）和VP-4（28,000）。放射性碘化病毒粒子蛋白的肽图比较表明它们之间不存在前体-产物关系。文中讨论了病毒基因组大小与不同病毒蛋白数量及大小之间的可能关系。