Department of Health Services Research & Policy, London School of Hygiene & Tropical Medicine, London, UK.
BMJ Qual Saf. 2012 Sep;21(9):737-45. doi: 10.1136/bmjqs-2011-001159.
Monitoring hospital mortality rates is widely recommended. However, the number of preventable deaths remains uncertain with estimates in England ranging from 840 to 40 000 per year, these being derived from studies that identified adverse events but not whether events contributed to death or shortened life expectancy of those affected.
Retrospective case record reviews of 1000 adults who died in 2009 in 10 acute hospitals in England were undertaken. Trained physician reviewers estimated life expectancy on admission, to identified problems in care contributing to death and judged if deaths were preventable taking into account patients' overall condition at that time.
Reviewers judged 5.2% (95% CI 3.8% to 6.6%) of deaths as having a 50% or greater chance of being preventable. The principal problems associated with preventable deaths were poor clinical monitoring (31.3%; 95% CI 23.9 to 39.7), diagnostic errors (29.7%; 95% CI 22.5% to 38.1%), and inadequate drug or fluid management (21.1%; 95% CI 14.9 to 29.0). Extrapolating from these figures suggests there would have been 11 859 (95% CI 8712 to 14 983) adult preventable deaths in hospitals in England. Most preventable deaths (60%) occurred in elderly, frail patients with multiple comorbidities judged to have had less than 1 year of life left to live.
The incidence of preventable hospital deaths is much lower than previous estimates. The burden of harm from preventable problems in care is still substantial. A focus on deaths may not be the most efficient approach to identify opportunities for improvement given the low proportion of deaths due to problems with healthcare.
监测医院死亡率被广泛推荐。然而,英国每年的可预防死亡人数仍不确定,估计值在 840 至 40000 人之间,这些数据来自于识别不良事件但未确定事件是否导致死亡或缩短受影响者预期寿命的研究。
对英格兰 10 家急性医院 2009 年死亡的 1000 名成年人进行回顾性病例记录审查。经过培训的医生审查员评估入院时的预期寿命,确定导致死亡的护理问题,并考虑到患者当时的整体状况,判断死亡是否可以预防。
审查员判断 5.2%(95%CI 3.8%至 6.6%)的死亡有 50%或更高的可能性是可以预防的。与可预防死亡相关的主要问题是临床监测不良(31.3%;95%CI 23.9%至 39.7%)、诊断错误(29.7%;95%CI 22.5%至 38.1%)和药物或液体管理不当(21.1%;95%CI 14.9%至 29.0%)。从这些数字推断,英格兰医院可能有 11859 名(95%CI 8712 至 14983 名)成年可预防死亡。大多数可预防死亡(60%)发生在患有多种合并症的年老、体弱患者身上,这些患者预计还剩下不到 1 年的寿命。
可预防的医院死亡发生率远低于先前的估计。由于医疗保健问题导致的可预防死亡的危害负担仍然很大。鉴于由于医疗保健问题导致的死亡比例较低,关注死亡可能不是识别改进机会的最有效方法。