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临床脂肪移植的分类:不同问题,不同解决方案。

A classification of clinical fat grafting: different problems, different solutions.

机构信息

Boston, Mass.; and Dallas, Texas From Back Bay Plastic Surgery and the University of Texas Southwestern Medical Center.

出版信息

Plast Reconstr Surg. 2012 Sep;130(3):511-522. doi: 10.1097/PRS.0b013e31825dbf8a.

DOI:10.1097/PRS.0b013e31825dbf8a
PMID:22929236
Abstract

BACKGROUND

Fat grafting has reemerged from a highly variable procedure to a technique with vast reconstructive and cosmetic potential. Largely because of a more disciplined and scientific approach to fat grafting as a transplantation event, early adopters of fat transplantation have begun to approach fat grafting as a process, using sound surgical transplantation principles: recipient preparation, controlled donor harvest, time-efficient transplantation, and proper postoperative care. Despite these principles, different fat grafting techniques yield impressive clinical outcomes.

METHODS

The essential variables of four types of fat grafting cases were identified and compared: harvesting, methods of cell processing, methods of transplantation, and management of the recipient site.

RESULTS

Each case differed for most of the variables analyzed. The two clinical drivers that most impacted these differences were the volume demands of the recipient site and whether the recipient site was healthy tissue or pathologic tissue. After these two drivers, a matrix classification of small-volume versus large-volume and regenerative versus nonregenerative cases yields four distinct categories.

CONCLUSIONS

Not all fat grafting is the same. Fat grafting, once thought to be a simple technique with variable results, is a much more complex procedure with at least four definable subtypes. By defining the essential differences in the recipient site, the key driver in fat transplantation, the proper selection of technique can be best chosen. In fat transplantation, different problems require different solutions.

摘要

背景

脂肪移植已从一种高度可变的手术演变为一种具有广泛重建和美容潜力的技术。由于对脂肪移植作为移植事件的方法更加规范和科学,脂肪移植的早期采用者已经开始将脂肪移植作为一个过程来对待,采用合理的外科移植原则:受区准备、受控供区采集、高效移植和适当的术后护理。尽管有这些原则,但不同的脂肪移植技术会产生令人印象深刻的临床效果。

方法

确定并比较了四种脂肪移植病例的基本变量:采集、细胞处理方法、移植方法和受区管理。

结果

大多数分析的变量在每种情况下都有所不同。影响这些差异的两个临床驱动因素是受区的体积需求以及受区是健康组织还是病理组织。在这两个驱动因素之后,对小体积与大体积以及再生与非再生病例进行矩阵分类,可以产生四个不同的类别。

结论

并非所有的脂肪移植都是相同的。脂肪移植曾经被认为是一种结果可变的简单技术,但实际上是一种更为复杂的过程,至少可以分为四种明确的亚型。通过定义脂肪移植中受区的基本差异,即脂肪移植的关键驱动因素,可以选择最合适的技术。在脂肪移植中,不同的问题需要不同的解决方案。

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