Lin Yan, Mu Dali, Zhang Xiaoyu, Li Haoran, Yao Yu
Department of Aesthetic and Reconstructive Breast Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Badachu Road, Shijingshan District, Beijing, 100144, People's Republic of China.
Aesthetic Plast Surg. 2023 Oct;47(5):1731-1739. doi: 10.1007/s00266-023-03367-2. Epub 2023 Apr 27.
Autologous adipose tissue has become increasingly popular in cosmetic and plastic reconstructive surgery, especially breast augmentation surgery. However, the volume retention rate after transplantation significantly varies and may be unsatisfactory. Many patients need two or more autologous fat graft breast augmentations to achieve the expected effect. There are currently no studies on optimal timing between fat injections.
We identified target patients with secondary or multiple autologous fat transplantations by inclusion and exclusion criteria and used three-dimensional scanning technology to calculate the volume retention. Patients were divided into two groups according to the dates of the first and second operations (group A: interoperative time < 120 days, group B: interoperative time ≥ 120 days). We used SPSS 26 for statistical calculations.
We included 161 patients in this retrospective study, with an average volume retention rate of 36.56% in group A (n = 85) and 27.45% in group B (n = 76). The independent sample t test showed that the volume retention rate in group A was higher than that in group B (P < 0.001). And the paired t test showed there is a significant improvement of volume retention rate after the second fat graft session (P < 0.001). Multivariate regression analysis showed that the interval time was an independent factor affecting the postoperative volume retention rate.
The interval time between autologous fat transplantation for augmentation mammaplasty was an independent factor affecting the postoperative volume retention rate. The postoperative volume retention rate of the < 120 days group was higher than that of the ≥ 120 days group.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
自体脂肪组织在美容整形和重建手术中越来越受欢迎，尤其是在隆胸手术中。然而，移植后的体积保留率差异很大，可能不尽人意。许多患者需要进行两次或更多次自体脂肪移植隆胸才能达到预期效果。目前尚无关于脂肪注射最佳时间间隔的研究。
我们通过纳入和排除标准确定了接受二次或多次自体脂肪移植的目标患者，并使用三维扫描技术计算体积保留率。根据首次和第二次手术日期将患者分为两组（A组：手术间隔时间<120天，B组：手术间隔时间≥120天）。我们使用SPSS 26进行统计计算。
本回顾性研究共纳入161例患者，A组（n = 85）的平均体积保留率为36.56%，B组（n = 76）为27.45%。独立样本t检验显示，A组的体积保留率高于B组（P < 0.001）。配对t检验显示，第二次脂肪移植术后体积保留率有显著提高（P < 0.001）。多因素回归分析显示，间隔时间是影响术后体积保留率的独立因素。
自体脂肪移植隆胸的间隔时间是影响术后体积保留率的独立因素。<120天组的术后体积保留率高于≥120天组。
证据等级IV：本刊要求作者为每篇文章指定证据等级。有关这些循证医学评级的完整描述，请参阅目录或作者在线指南www.springer.com/00266 。
