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队列研究简介:QSkin 阳光与健康研究。

Cohort profile: the QSkin Sun and Health Study.

机构信息

Population Health Department, Queensland Institute of Medical Research, Queensland, Australia and University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.

出版信息

Int J Epidemiol. 2012 Aug;41(4):929-929i. doi: 10.1093/ije/dys107.

DOI:10.1093/ije/dys107
PMID:22933644
Abstract

The QSkin Sun and Health Study comprises a cohort of 43 794 men and women aged 40-69 years randomly sampled from the population of Queensland, Australia in 2011. The cohort was established to study the development of skin cancer and melanoma in the population with the highest reported incidence of these diseases in the world. At baseline, besides demographic items and general medical history, information about standard pigmentary characteristics (including hair and eye colour, freckling tendency, tanning ability and propensity to sunburn), past and recent history of sun exposure and sunburns, sun protection behaviours, use of tanning beds and history of skin cancer was collected by self-completed questionnaire. Participants have given their consent for data linkage to the universal national health insurance scheme and for linkage to cancer registries and pathology databases, thus ensuring complete ascertainment of all future skin cancer and melanoma occurrences and medical treatments and other cancer events. Linkage to these registers will occur at predetermined intervals. Approval to access QSkin data can be obtained on application to the study investigators and submission of a formal research plan that has previous approval from the human research ethics committee of the applicant's institution.

摘要

QSkin 阳光与健康研究包括一个队列,其中有 43794 名年龄在 40-69 岁的男性和女性,他们是 2011 年从澳大利亚昆士兰州的人群中随机抽样的。该队列的建立是为了研究皮肤癌和黑色素瘤在世界上发病率最高的人群中的发展情况。在基线时,除了人口统计学项目和一般病史外,还通过自我完成的问卷收集了有关标准色素特征(包括头发和眼睛颜色、雀斑倾向、晒黑能力和晒伤倾向)、过去和最近的阳光暴露和晒伤史、防晒行为、使用晒黑床和皮肤癌史的信息。参与者已同意将数据与全民健康保险计划链接,并与癌症登记处和病理数据库链接,从而确保对所有未来的皮肤癌和黑色素瘤发生以及医疗和其他癌症事件的完全确定。将与这些登记处进行链接,链接时间间隔是预先确定的。访问 QSkin 数据的批准可在向研究调查人员申请时获得,并提交一份正式的研究计划,该计划必须事先获得申请人机构的人类研究伦理委员会的批准。

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