Bunjean Karun, Sukkasem Kamonchanok, Noppacroh Natchaporn, Yamkaew Nattapol, Janthayanont Dusit, Theerapancharern Werapol, Chokkanchitchai Surachai, Moungthong Greetha
Department of Otolaryngology, Phramongkutklao College of Medicine, Bangkok, Thailand.
J Med Assoc Thai. 2012 May;95 Suppl 5:S63-8.
Allergic rhinitis is a common problem in many countries. The incidence of Allergic rhinitis is about 10-25% of the population and increasing worldwide especially in large cities where air pollution is the main problem causing respiratory illness. In Thailand, the surveys of allergic rhinitis on children were found about 13-44% while the prevalence of allergic rhinitis in Thai adults was as high as 20%. The information of the prevalence of allergic rhinitis in the suburban area has not been continuously done especially in the adult population.
To present study the prevalence of allergic rhinitis and other atopic diseases and to determine the aeroallergen sensitivity of allergic patients in suburban area.
Observational descriptive cross-sectional study as one-stage cluster sampling, Using ISAAC questionnaires interviewed adults at War Intaram community, Hua Raeu, Phra Nakhon Si Ayutthaya District, Phra Nakhon Si Ayutthaya Province, Thailand during September-October 2008. Participants who had allergic rhinitis symptoms described in the questionnaires were enrolled to perform the skin prick test voluntary to determine the aeroallergen sensitivity.
There were 324 subjects, female 64.8% and male 35.2%. Age ranges between 20-66 years old (mean 42.2). The prevalence of allergic rhinitis, asthma and chronic pruritic rash were 37.7%, 16%, 21.3% and history of allergic rhinitis, asthma and chronic pruritic rash within 12 months were 32.1%, 10.5%, 17.3%. The sensitized allergen was mixed mite (62.2%), mixed cockroach (61.1%), house dust (48.9%), cat (37.8%), Johnson glass (30.0%), dog (20.0%), careless weed (20.0%), mixed mold (12.2%), cotton (7.8%) and feather (6.7%).
The present study revealed that the prevalence of allergic rhinitis and atopic diseases has been increasing in number when compared with previous reports. The most common sensitized allergen was Mite mix, similar to other studies, but mixed cockroach was found significantly higher.
变应性鼻炎在许多国家都是一个常见问题。变应性鼻炎的发病率约占总人口的10%-25%,且在全球范围内呈上升趋势,尤其是在空气污染是导致呼吸道疾病主要问题的大城市。在泰国,对儿童变应性鼻炎的调查发现发病率约为13%-44%,而泰国成年人变应性鼻炎的患病率高达20%。关于郊区变应性鼻炎患病率的信息尚未持续开展,尤其是在成年人群体中。
研究郊区变应性鼻炎及其他特应性疾病的患病率,并确定变应性患者的气传变应原敏感性。
采用观察性描述性横断面研究,采用单阶段整群抽样,于2008年9月至10月期间,使用国际儿童哮喘和变应性疾病研究(ISAAC)问卷对泰国大城府大城府县华叻区瓦因他拉姆社区的成年人进行访谈。对问卷中描述有变应性鼻炎症状的参与者自愿进行皮肤点刺试验,以确定气传变应原敏感性。
共有324名受试者,女性占64.8%,男性占35.2%。年龄在20-66岁之间(平均42.2岁)。变应性鼻炎、哮喘和慢性瘙痒性皮疹的患病率分别为37.7%、16%、21.3%,12个月内有变应性鼻炎、哮喘和慢性瘙痒性皮疹病史的分别为32.1%、10.5%、17.3%。致敏变应原依次为混合螨(62.2%)、混合蟑螂(61.1%)、屋尘(48.9%)、猫(37.8%)、约翰逊玻璃(30.0%)、狗(20.0%)、莠草(20.0%)、混合霉菌(12.2%)、棉花(7.8%)和羽毛(6.7%)。
本研究表明,与以往报告相比,变应性鼻炎和特应性疾病的患病率呈上升趋势。最常见的致敏变应原是混合螨,与其他研究相似,但混合蟑螂的比例明显更高。