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2011 年中国一名男孩感染的欧洲类禽流感 H1N1 猪流感病毒的抗原性和遗传学特征。

Antigenic and genetic characterization of a European avian-like H1N1 swine influenza virus from a boy in China in 2011.

机构信息

Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China.

出版信息

Arch Virol. 2013 Jan;158(1):39-53. doi: 10.1007/s00705-012-1423-7. Epub 2012 Aug 31.

Abstract

Cross-species transmission of influenza A viruses from swine to human occurs occasionally. In 2011, an influenza A H1N1 virus, A/Jiangsu/ALS1/2011 (JS/ALS1/2011), was isolated from a boy who suffered from severe pneumonia in China. The virus is closely related antigenically and genetically to avian-like swine H1N1 viruses that have recently been circulating in pigs in China and that were initially detected in European pig populations in 1979. The isolation of JS/ALS1/2011 provides additional evidence that swine influenza viruses can occasionally infect humans and emphasizes the importance of reinforcing influenza virus surveillance in both pigs and humans.

摘要

甲型流感病毒偶尔会在物种间从猪传播给人类。2011 年,中国一名患有严重肺炎的男孩体内分离出一株甲型 H1N1 流感病毒,称为 A/江苏/ALS1/2011(JS/ALS1/2011)。该病毒在抗原性和遗传学上与最近在中国猪群中流行的类似禽流感的猪 H1N1 病毒密切相关,这些病毒最初于 1979 年在欧洲猪群中检测到。JS/ALS1/2011 的分离为猪流感病毒偶尔感染人类提供了更多证据,并强调了加强猪和人群中流感病毒监测的重要性。

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