多功能方法合成 α-烷氧基氨基甲酸酯和刺激响应性的醇释放。
Versatile approach to α-alkoxy carbamate synthesis and stimulus-responsive alcohol release.
机构信息
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
出版信息
Org Biomol Chem. 2012 Oct 21;10(39):7980-5. doi: 10.1039/c2ob26571k.
Abstract
A series of α-alkoxy carbamates that cleave under mild conditions to release alcohols has been synthesized through a multicomponent process. The relationship between structural features in these compounds and the rate of alcohol release in the presence of basic hydrogen peroxide has been studied. The preparation of carbamates that cleave under other conditions has been demonstrated.
摘要
通过多组分反应合成了一系列在温和条件下断裂以释放醇的α-烷氧基氨基甲酸酯。研究了这些化合物的结构特征与碱性过氧化氢存在下醇释放速率之间的关系。还证明了在其他条件下断裂的氨基甲酸酯的制备。
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